Evidence map›Paper›PMID 35759871›Full record

ReviewAnnual review of microbiology2022

Harnessing the Immune Response to Fungal Pathogens for Vaccine Development.

Amariliz Rivera, Jennifer Lodge, Chaoyang Xue

Open access · greenAbstract readReview
In one paragraph

Review in Annual review of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Peripheral blood CD4The Journal of infection · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. From soil to clinic: current advances in understandingMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  12. Review
  13. Review
  14. Review
  15. Vaccine Strategies for Cryptococcus neoformans.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  16. Construction ofVaccines · 2023
    Article
  17. Vaccination with aInfection and immunity · 2023
    Article
  18. Review
  19. Immunity to fungi in the lung.Seminars in immunology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Amariliz RiveraDepartment of Pediatrics and Center for Immunity and Inflammation, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA; email: riveraam@njms.rutgers.edu.
Jennifer LodgeDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Chaoyang XuePublic Health Research Institute and Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA; email: xuech@njms.rutgers.edu.
Rutgers HealthRutgers, The State University of New Jersey · USWashington University in St. Louis · US

Funding

Preclinical studies of a Cryptococcus vaccine for AIDS patientsR01AI125045 · NIAID · WASHINGTON UNIVERSITY · PI LEVITZ, STUART MICHAEL, LODGE, JENNIFER K. · 2016 to 2025
$7.1M
Mechanisms of vaccine protection against AIDS-associated Cryptococcus infectionR01AI141368 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Amariliz Rivera, Chaoyang Xue · 2019 to 2026
$5.4M
The role of inositol in Cryptococcus biology and pathogenesisR01AI123315 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Chaoyang Xue · 2017 to 2026
$5.0M
Rutgers Optimizes Innovation (ROI) ProgramU01HL150852 · NHLBI · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI LIBUTTI, STEVEN K., PANETTIERI, REYNOLD ALEXANDER · 2019 to 2022
$4.4M
ROLE OF CELL WALL INTEGRITY IN ECHINOCANDIN RESISTANCE IN C. NEOFORMANSR01AI123407 · NIAID · WASHINGTON UNIVERSITY · PI DONLIN, MAUREEN J, LODGE, JENNIFER K. · 2017 to 2021
$1.9M
Lipid flippase in echinocandin drug resistance in Cryptococcus neoformansR21AI154318 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI XUE, CHAOYANG · 2020 to 2021
$430k
NHLBI NIH HHS U01 HL150852NIAID NIH HHS R01 AI123315NIAID NIH HHS R01 AI123407NIAID NIH HHS R01 AI125045NIAID NIH HHS R01 AI141368NIAID NIH HHS R21 AI154318
6 · The paper itself

Abstract

Invasive fungal infections are emerging diseases that kill over 1.5 million people per year worldwide. With the increase of immunocompromised populations, the incidence of invasive fungal infections is expected to continue to rise. Vaccines for viral and bacterial infectious diseases have had a transformative impact on human health worldwide. However, no fungal vaccines are currently in clinical use. Recently, interest in fungal vaccines has grown significantly. One

Indexed as

Fungal VaccinesInvasive Fungal InfectionsVaccinesAnimalsHumansImmunityMiceVaccine DevelopmentFungal VaccinesVaccinesadaptive immunityfungal infectionsfungal vaccinesinnate immunityT cellstrained immunity

Identifiers

PMID35759871
PMCPMC11926770
OpenAlexW4283653679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.