Evidence map›Paper›PMID 35759808›Full record

ArticleJournal of infection and public health2022

Machine learning decision tree algorithm role for predicting mortality in critically ill adult COVID-19 patients admitted to the ICU.

Alyaa Elhazmi, Awad Al-Omari, Hend Sallam, Hani N Mufti, Ahmed A Rabie, Mohammed Alshahrani, Ahmed Mady, Adnan Alghamdi, Ali Altalaq, Mohamed H Azzam and 12 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of infection and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  4. The impact of knowledge of hospitalization on mortality predictions.Health services & outcomes research methodology · 2025
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  11. 21st century critical care medicine: An overview.World journal of critical care medicine · 2024
    Review
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  17. A Multi-Layered GRU Model for COVID-19 Patient Representation and Phenotyping from Large-Scale EHR Data.ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Alyaa ElhazmiDepartment of Critical Care, Dr. Sulaiman Al-Habib Medical Group, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia. Electronic address: a.m.haz@live.com.
Awad Al-OmariResearch Center, Dr. Sulaiman Alhabib Medical Group, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Hend SallamDepartment of Adult Critical Care Medicine, King Faisal Specialist Hospital & Research Centre, Saudi Arabia.
Hani N MuftiSection of Cardiac Surgery, Department of Cardiac Sciences, King Faisal Cardiac Center, King Abdulaziz Medical City, MNGHA-WR, Jeddah, Saudi Arabia; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia. King Abdullah International Medical Research Center, Jeddah, Saudi Arabia Intensive Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Ahmed A RabieCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia. Electronic address: drarabie@ksmc.med.sa.
Mohammed AlshahraniEmergency and Critical Care Department, King Fahad Hospital of The University, Imam Abdul Rahman ben Faisal University, Dammam, Saudi Arabia.
Ahmed MadyCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia; Department of Anesthesiology and Intensive Care, Tanta University Hospitals, Tanta, Egypt.
Adnan AlghamdiPrince Sultan Military Medical City, Military Medical Services, Ministry of Defence, Riyadh, Saudi Arabia.
Ali AltalaqPrince Sultan Military Medical City, Military Medical Services, Ministry of Defence, Riyadh, Saudi Arabia.
Mohamed H AzzamIntensive Care Department, King Abdullah Medical Complex, Jeddah, Saudi Arabia.
Anees SindiDepartment of Anesthesia and Critical Care, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Ayman KharabaDepartment of Critical Care, King Fahad Hospital, Al Medina Al Monawarah, Saudi Arabia.
Zohair A Al-AseriDepartments Of Emergency Medicine and Critical Care, College of Medicine, King Saud University, Riyadh, Saudi Arabia; College Of Medicine, Dar Al Uloom University, Riyadh, Saudi Arabia.
Ghaleb A AlmekhlafiPrince Sultan Military Medical City, Military Medical Services, Ministry of Defence, Riyadh, Saudi Arabia.
Wail TashkandiDepartment of Critical Care, Fakeeh Care Group, Jeddah, Saudi Arabia; Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia.
Saud A AlajmiPrince Sultan Military Medical City, Military Medical Services, Ministry of Defence, Riyadh, Saudi Arabia.
Fahad FaqihiCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Abdulrahman AlharthyCritical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.
Jaffar A Al-TawfiqInfectious Disease Unit, Specialty Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia. Infectious Disease Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Infectious Disease Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Rami Ghazi MelibariDepartment of Critical Care, King Abdullah Medical City, Makah, Saudi Arabia.
Waleed Al-HazzaniDepartment of Medicine, McMaster University, Hamilton, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.
Yaseen M ArabiCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Intensive Care Department, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease-19 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is currently a major cause of intensive care unit (ICU) admissions globally. The role of machine learning in the ICU is evolving but currently limited to diagnostic and prognostic values. A decision tree (DT) algorithm is a simple and intuitive machine learning method that provides sequential nonlinear analysis of variables. It is simple and might be a valuable tool for bedside physicians during COVID-19 to predict ICU outcomes and help in critical decision-making like end-of-life decisions and bed allocation in the event of limited ICU bed capacities. Herein, we utilized a machine learning DT algorithm to describe the association of a predefined set of variables and 28-day ICU outcome in adult COVID-19 patients admitted to the ICU. We highlight the value of utilizing a machine learning DT algorithm in the ICU at the time of a COVID-19 pandemic.

methodsThis was a prospective and multicenter cohort study involving 14 hospitals in Saudi Arabia. We included critically ill COVID-19 patients admitted to the ICU between March 1, 2020, and October 31, 2020. The predictors of 28-day ICU mortality were identified using two predictive models: conventional logistic regression and DT analyses.

resultsThere were 1468 critically ill COVID-19 patients included in the study. The 28-day ICU mortality was 540 (36.8 %), and the 90-day mortality was 600 (40.9 %). The DT algorithm identified five variables that were integrated into the algorithm to predict 28-day ICU outcomes: need for intubation, need for vasopressors, age, gender, and PaO2/FiO2 ratio.

conclusionDT is a simple tool that might be utilized in the ICU to identify critically ill COVID-19 patients who are at high risk of 28-day ICU mortality. However, further studies and external validation are still required.

Indexed as

COVID-19AdultAlgorithmsCohort StudiesCritical IllnessDecision TreesHumansIntensive Care UnitsMachine LearningPandemicsProspective StudiesRetrospective StudiesSARS-CoV-2COVID-19Decision treeICUPredictorsSARS-Cov2

Identifiers

PMID35759808
PMCPMC9212964

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.