Evidence map›Paper›PMID 35759257›Full record

ArticleAngewandte Chemie (International ed. in English)2022

Light-Activated Membrane Transport in Polymeric Cell-Mimics.

Shoupeng Cao, Lucas Caire da Silva, Katharina Landfester

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Thermally Driven Dynamic Behaviors in Polymeric Vesicles.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Emergent Behavior of a Photoswitchable Solute in a Biphasic Solvent System.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  11. Review
  12. Review
  13. Programmable Enzymatic Reaction Network in Artificial Cell-Like Polymersomes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  14. Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  15. Article
  16. Article
  17. Biomimetic behaviors in hydrogel artificial cells through embedded organelles.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Review
  20. Light-Activated Membrane Transport in Polymeric Cell-Mimics.Angewandte Chemie (International ed. in English) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shoupeng CaoMax Planck Institute for Polymer Research, 55128, Mainz, Germany.ORCID 0000-0002-5856-2407
Lucas Caire da SilvaMax Planck Institute for Polymer Research, 55128, Mainz, Germany.
Katharina LandfesterMax Planck Institute for Polymer Research, 55128, Mainz, Germany.ORCID 0000-0001-9591-4638
Max Planck Institute for Polymer Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant polymersomes are versatile and stable biomimetic compartments that are ideal for building cell-like systems. However, the transport of hydrophilic molecules across the membrane, which controls the function of cell-like systems, is limited by the low permeability of polymeric bilayers. Therefore, mechanisms to control the permeability of polymersomes are necessary to create functional cell-like systems. Here, we describe the design of giant polymersomes equipped with spiropyran-based permeability modulators. Photo-isomerization of the modulators leads to perturbation of the polymer membrane, resulting in increased permeability. The photoactivated polymersomes were used to construct two cell-like systems controlled by light-activated transport of hydrophilic molecules. First, we designed an enzymatic micro-reactor activated by light irradiation. Second, we constructed a hybrid coacervate-in-polymersome system that mimics the adaptive formation of biological condensates in cells.

Indexed as

PolymersBiological TransportHydrophobic and Hydrophilic InteractionsPermeabilityPolymersCoacervatesLight-ActivationMulti-CompartmentsPolymersomesSynthetic Cells

Identifiers

PMID35759257
PMCPMC9542181
OpenAlexW4283582107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.