Evidence map›Paper›PMID 35759072›Full record

ArticleMetabolic brain disease2022

Exogenous hydrogen sulfide restores CSE and CBS but no 3-MST protein expression in the hypothalamus and brainstem after severe traumatic brain injury.

Saúl Huerta de la Cruz, Erick J Rodríguez-Palma, Cindy L Santiago-Castañeda, Jesús H Beltrán-Ornelas, Araceli Sánchez-López, Luisa Rocha, David Centurión

Abstract read
PubMed Publisher
In one paragraph

Article in Metabolic brain disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Sodium hydrogen sulfide restores HInflammopharmacology · 2025
    Article
  3. Article
  4. Altered Production and Cellular Levels of Hydrogen Sulfide (HPathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
  5. Age-dependent effects of HFrontiers in psychiatry · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Saúl Huerta de la CruzDepartamento de Farmacobiología, Cinvestav-Coapa, Mexico City, Mexico.ORCID 0000-0002-5968-9506
Erick J Rodríguez-PalmaNeurobiology of Pain Laboratory, Departamento de Farmacobiología, Cinvestav, Sede Sur, Mexico City, Mexico.ORCID 0000-0002-9940-363X
Cindy L Santiago-CastañedaDepartamento de Farmacobiología, Cinvestav-Coapa, Mexico City, Mexico.ORCID 0000-0002-9105-9547
Jesús H Beltrán-OrnelasDepartamento de Farmacobiología, Cinvestav-Coapa, Mexico City, Mexico.ORCID 0000-0003-2075-8313
Araceli Sánchez-LópezDepartamento de Farmacobiología, Cinvestav-Coapa, Mexico City, Mexico.ORCID 0000-0002-4877-297X
Luisa RochaDepartamento de Farmacobiología, Cinvestav-Coapa, Mexico City, Mexico.ORCID 0000-0003-4495-9427
David CenturiónDepartamento de Farmacobiología, Cinvestav-Coapa, Mexico City, Mexico. dcenturi@cinvestav.mx.ORCID 0000-0003-4030-8491
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

Brain Injuries, TraumaticHydrogen SulfideAnimalsBrain StemCystathionineCystathionine beta-SynthaseHypothalamusCystathionineCystathionine beta-SynthaseHydrogen Sulfide3-mercaptopiruvate sulfurtransferaseCystathionine-β-synthaseCystathionine-γ-lyaseHydrogen sulfideTraumatic brain injury

Identifiers

PMID35759072
OpenAlexW4283587866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.