Evidence map›Paper›PMID 35758831›Full record

SynthesisArchives of endocrinology and metabolism

Association of methylenetetrahydrofolate reductase (

Rui Yang, Danhua Pu, Rongrong Tan, Jie Wu

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Archives of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Genotype Combinations and Genetic Risk Score Analyses ofCurrent issues in molecular biology · 2025
    Article
  3. Study of theDiagnostics (Basel, Switzerland) · 2025
    Article
  4. Children (Basel, Switzerland) · 2025
    Review
  5. MTHFR as a Novel Candidate Marker for Litter Size in Rabbits.Animals : an open access journal from MDPI · 2024
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rui Yang *State Key Laboratory of Reproductive Medicine, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Jiangsu Women and Children Health Hospital, Nanjing, China.
Danhua Pu *State Key Laboratory of Reproductive Medicine, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Jiangsu Women and Children Health Hospital, Nanjing, China.
Rongrong TanState Key Laboratory of Reproductive Medicine, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Jiangsu Women and Children Health Hospital, Nanjing, China.
Jie WuState Key Laboratory of Reproductive Medicine, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Jiangsu Women and Children Health Hospital, Nanjing, China, wujiemd@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have shown that two common methylenetetrahydrofolate reductase (

Indexed as

HypothyroidismMethylenetetrahydrofolate Reductase (NADPH2)Case-Control StudiesGenetic Predisposition to DiseaseHumansPolymorphism, GeneticPolymorphism, Single NucleotideRisk FactorsMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, humanmethylenetetrahydrofolate reductase (polymorphismriskThyroid dysfunction

Identifiers

PMID35758831
PMCPMC10697641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.