Local Delivery of Streptomycin in Microcontainers Facilitates Colonization of Streptomycin-Resistant Escherichia coli in the Rat Colon.
Anders M Torp, Khorshid Kamguyan, Juliane F Christfort, Katja Ann Kristensen, Priscila Guerra, Noëmie Daniel, Line Hagner Nielsen, Kinga Zòr, Benoit Chassaing, Anja Boisen and 2 more
Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 3 institutions in 3 countries.
Anders M TorpThe National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Khorshid KamguyanDepartment of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Juliane F ChristfortDepartment of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Katja Ann KristensenThe National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Priscila GuerraThe National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Noëmie DanielINSERM U1016, Team "Mucosal Microbiota in Chronic Inflammatory Diseases," CNRS UMR 8104, Université de Paris, Paris, France.
Line Hagner NielsenDepartment of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Kinga ZòrDepartment of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Benoit ChassaingINSERM U1016, Team "Mucosal Microbiota in Chronic Inflammatory Diseases," CNRS UMR 8104, Université de Paris, Paris, France.ORCID 0000-0002-4285-769X
Anja BoisenDepartment of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.
Martin I BahlThe National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Tine Rask LichtThe National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-6399-9574
Technical University of Denmark · DKFood Research Institute · SKCentre National de la Recherche Scientifique · FR
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Oral antibiotic treatment is often applied in animal studies in order to allow establishment of an introduced antibiotic-resistant bacterium in the gut. Here, we compared the application of streptomycin dosed orally in microcontainers to dosage through drinking water. The selective effect on a resistant bacterial strain, as well as the effects on fecal, luminal, and mucosal microbiota composition, were investigated. Three groups of rats (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Local Delivery of Streptomycin in Microcontainers Facilitates Colonization of Streptomycin-Resistant Escherichia coli in the Rat Colon. · full record | OpenQuestion