Evidence map›Paper›PMID 35758758›Full record

ArticleApplied and environmental microbiology2022

Development of a Versatile, Low-Cost Electrochemical System to Study Biofilm Redox Activity at the Micron Scale.

Alexander D Klementiev, Marvin Whiteley

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander D KlementievSchool of Biological Sciences, Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0001-7249-2532
Marvin WhiteleySchool of Biological Sciences, Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0002-4933-9983
Georgia Institute of Technology · US

Funding

Metabolite sensing in a polymicrobial infectionR01DE020100 · NIDCR · UNIVERSITY OF TEXAS AT AUSTIN · PI WHITELEY, MARVIN · 2011 to 2022
$3.3M
HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) DE023193HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) DE029415HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM116547NIDCR NIH HHS R01 DE020100
6 · The paper itself

Abstract

Spatially resolving chemical landscapes surrounding microbial communities can provide insight into chemical interactions that dictate cellular physiology. Electrochemical techniques provide an attractive option for studying these interactions due to their robustness and high sensitivity. Unfortunately, commercial electrochemical platforms that are capable of measuring chemical activity on the micron scale are often expensive and do not easily perform multiple scanning techniques. Here, we report development of an inexpensive electrochemical system that features a combined micromanipulator and potentiostat component capable of scanning surfaces while measuring molecular concentrations or redox profiles. We validate this experimental platform for biological use with a two-species biofilm model composed of the oral bacterial pathogen Aggregatibacter actinomycetemcomitans and the oral commensal Streptococcus gordonii. We measure consumption of H

Indexed as

BiofilmsHydrogen PeroxideAggregatibacter actinomycetemcomitansOxidation-ReductionStreptococcus gordoniiHydrogen PeroxideAggregatibacterbiofilmelectrochemistryPseudomonas aeruginosaredoxStreptococcustopography

Identifiers

PMID35758758
PMCPMC9328185
OpenAlexW4283581470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.