Evidence map›Paper›PMID 35758648›Full record

ArticleBJPsych open2022

Comparison of capability and health-related quality of life instruments in capturing aspects of mental well-being in people with schizophrenia and depression.

Timea Mariann Helter, Joanna Coast, Agata Łaszewska, Tanja Stamm, Judit Simon

Abstract read
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Article in BJPsych open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Cost-Effectiveness of Positive Memory Training (PoMeT) for the Treatment of Depression in Schizophrenia.International journal of environmental research and public health · 2022
    Trial
  3. Psychometric properties of the ICECAP-SCM capability-wellbeing measure in specialist palliative care units in Austria.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  4. Population normative data for OxCAP-MH capability scores.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  5. Article
  6. Evaluating health-related quality of life and subjective wellbeing among infertility patients: a cross-sectional study in mainland China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  7. Article
  8. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Timea Mariann HelterDepartment of Health Economics, Center for Public Health, Medical University of Vienna, Austria.ORCID https://orcid.org/0000-0002-2696-2553
Joanna CoastHealth Economics Bristol, Population Health Sciences, Bristol Medical School, University of Bristol, UK.
Agata ŁaszewskaDepartment of Health Economics, Center for Public Health, Medical University of Vienna, Austria.
Tanja StammSection for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Austria; and Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria.
Judit SimonDepartment of Health Economics, Center for Public Health, Medical University of Vienna, Austria; and Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.ORCID https://orcid.org/0000-0001-9279-8627

Funding

Wellcome TrustWellcome Trust 205384/Z/16/Z
6 · The paper itself

Abstract

backgroundThere is increasing evidence that assessing outcomes in terms of capability provides information beyond that of health-related quality of life (HRQoL) for outcome evaluation in mental health research and clinical practice.

aimsTo assess similarities and differences in the measurement properties of the ICECAP-A capability measure and Oxford Capabilities Questionnaire for Mental Health (OxCAP-MH) in people with schizophrenia experiencing depression, and compare these measurement properties with those of (a) the EuroQol EQ-5D-5L and EuroQol Visual Analogue Scale (EQ-VAS) and (b) mental health-specific (disease-specific) measures.

methodUsing data for 100 patients from the UK, measurement properties were compared using correlation analyses, Bland-Altman plots and exploratory factor analysis. Responsiveness was assessed by defining groups who worsened, improved or remained unchanged, based on whether there was a clinically meaningful change in the instrument scores between baseline and 9-month follow-up assessments.

resultsThe two capability instruments had stronger convergent validity with each other (Spearman's rho = 0.677) than with the HRQoL (rho = 0.354-0.431) or the mental health-specific (rho = 0.481-0.718) instruments. The OxCAP-MH tended to have stronger correlations with mental health-specific instruments than the ICECAP-A, whereas the ICECAP-A had slightly stronger correlation with the EQ-VAS. Change scores on the capability instruments correlated weakly with change scores on the HRQoL scales (rho = 0.131-0.269), but moderately with those on mental health-specific instruments for the ICECAP-A (rho = 0.355-0.451) and moderately/strongly on the OxCAP-MH (rho = 0.437-0.557).

conclusionsAssessing outcomes in terms of capabilities for people with schizophrenia and depression provided more relevant, mental health-specific information than the EQ-5D-5L or the EQ-VAS. The ICECAP-A and the OxCAP-MH demonstrated similar psychometric properties, but the OxCAP-MH was more correlated with disease-specific instruments.

Indexed as

Capability approachEQ-5D-5LICECAP-AOxCAP-MHschizophrenia

Identifiers

PMID35758648
PMCPMC9301777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.