Evidence map›Paper›PMID 35758630›Full record

ArticleBJPsych open2022

The interplay between psychopathological symptoms: transdiagnostic cross-lagged panel network model.

UnYoung Chavez-Baldini, Karin Verweij, Derek de Beurs, Claudi Bockting, Anja Lok, Arjen L Sutterland, Geeske van Rooijen, Guido van Wingen, Damiaan Denys, Nienke Vulink and 1 more

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Linking spontaneous speech, cognition, and psychopathology across affective and psychotic disorders: A network approach.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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  14. Exploring the dynamics of perioperative symptom networks in colorectal cancer patients: a cross-lagged panel network analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

UnYoung Chavez-BaldiniDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0001-5613-513X
Karin VerweijDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0001-9868-7821
Derek de BeursDepartment of Epidemiology, Netherlands Institute of Mental Health and Addiction (Trimbos Institute), The Netherlands.ORCID https://orcid.org/0000-0002-0166-6897
Claudi BocktingDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-9220-9244
Anja LokDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-0560-9603
Arjen L SutterlandDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0001-9206-2492
Geeske van RooijenDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.
Guido van WingenDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0003-3076-5891
Damiaan DenysDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-3191-3844
Nienke VulinkDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0001-8991-9627
Dorien NiemanDepartment of Psychiatry, Amsterdam University Medical Center, University of Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-9846-4254
University of Amsterdam · NLTrimbos Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent paradigm shifts suggest that psychopathology manifests through dynamic interactions between individual symptoms.

aimsTo investigate the longitudinal relationships between symptoms in a transdiagnostic sample of patients with psychiatric disorders.

methodA two-wave, cross-lagged panel network model of 15 nodes representing symptoms of depression, (social) anxiety and attenuated psychotic symptoms was estimated, using baseline and 1-year follow-up data of 222 individuals with psychiatric disorders. Centrality indices were calculated to determine important predictors and outcomes.

resultsOur results demonstrated that the strongest relationships in the network were between (a) more suicidal ideation predicting more negative self-view, and (b) autoregressive relationships of social anxiety symptoms positively reinforcing themselves. Negative self-view was the most predictable node in the network as it had the highest 'in-expected influence' centrality, and may be an important transdiagnostic outcome symptom.

conclusionsThe results give insight into longitudinal interactions between symptoms, which interact in ways that do not adhere to broader diagnostic categories. Our results suggest that self-view can also be a transdiagnostic outcome of psychopathology rather than just a predictor, as is normally posited, and may especially have an important relationship with suicidal ideation. Overall, our study demonstrates the dynamic complexity of psychopathology, and further supports the importance of investigating symptom interactions of different psychopathological dimensions over time and across disorders.

Indexed as

longitudinalnetwork analysispsychopathologysymptom networkTransdiagnostic

Identifiers

PMID35758630
PMCPMC9301766
OpenAlexW4283587965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.