Evidence map›Paper›PMID 35758534›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2022

Real-Time Feedback-Driven Single-Particle Tracking: A Survey and Perspective.

Bertus van Heerden, Nicholas A Vickers, Tjaart P J Krüger, Sean B Andersson

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Perspective: An outlook on fluorescence tracking.The Journal of chemical physics · 2025
    Article
  7. Article
  8. Article
  9. Biophysical reviews · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Bertus van HeerdenDepartment of Physics, University of Pretoria, Pretoria, 0002, South Africa.ORCID 0000-0002-6769-0697
Nicholas A VickersDepartment of Mechanical Engineering, Boston University, Boston, MA, 02215, USA.ORCID 0000-0002-2293-9671
Tjaart P J KrügerDepartment of Physics, University of Pretoria, Pretoria, 0002, South Africa.ORCID 0000-0002-0801-6512
Sean B AnderssonDepartment of Mechanical Engineering, Boston University, Boston, MA, 02215, USA.ORCID 0000-0001-7575-3507
Boston University · USUniversity of Pretoria · ZA

Funding

Joint estimation of motion model, model parameters, and particle trajectories in single particle trackingR01GM117039 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI ANDERSSON, SEAN B. · 2017 to 2021
$1.7M
NIGMS NIH HHS 5R01GM117039NIGMS NIH HHS R01 GM117039
6 · The paper itself

Abstract

Real-time feedback-driven single-particle tracking (RT-FD-SPT) is a class of techniques in the field of single-particle tracking that uses feedback control to keep a particle of interest in a detection volume. These methods provide high spatiotemporal resolution on particle dynamics and allow for concurrent spectroscopic measurements. This review article begins with a survey of existing techniques and of applications where RT-FD-SPT has played an important role. Each of the core components of RT-FD-SPT are systematically discussed in order to develop an understanding of the trade-offs that must be made in algorithm design and to create a clear picture of the important differences, advantages, and drawbacks of existing approaches. These components are feedback tracking and control, ranging from simple proportional-integral-derivative control to advanced nonlinear techniques, estimation to determine particle location from the measured data, including both online and offline algorithms, and techniques for calibrating and characterizing different RT-FD-SPT methods. Then a collection of metrics for RT-FD-SPT is introduced to help guide experimentalists in selecting a method for their particular application and to help reveal where there are gaps in the techniques that represent opportunities for further development. Finally, this review is concluded with a discussion on future perspectives in the field.

Indexed as

AlgorithmsSingle Molecule ImagingFeedbackSpectrum Analysisactive feedback trackingsingle molecule spectroscopysingle-particle tracking

Identifiers

PMID35758534
PMCPMC9308725
OpenAlexW3213584427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.