Evidence map›Paper›PMID 35758051›Full record

ArticleBioengineered2022

IL-17A deletion reduces sevoflurane-induced neurocognitive impairment in neonatal mice by inhibiting NF-κB signaling pathway.

Qi Zhang, Yanan Li, Chunping Yin, Mingyang Gao, Jiaxu Yu, Junfei Guo, Xiaohui Xian, Zhiyong Hou, Qiujun Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qi ZhangDepartment of Anesthesiology, Hebei Children's Hospital Affiliated to Hebei Medical University, Shijiazhuang, Hebei, China.
Yanan LiDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Chunping YinDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Mingyang GaoDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jiaxu YuDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Junfei GuoDepartment of Orthopaedics, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Xiaohui XianDepartment of Pathophysiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Zhiyong HouDepartment of Orthopaedics, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Qiujun WangDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Hebei Medical University · CNThird Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the role of IL-17A in sevoflurane-inducedneurocognitive impairment in neonatal mice. Seventy-two wild-type (WT) and 42 IL-17A knockout (KO) neonatal mice were randomly divided into WT (

Indexed as

Interleukin-17NF-kappa BAnimalsAnimals, NewbornChemokinesInterleukin-6MiceSevofluraneSignal TransductionChemokinesInterleukin-17Interleukin-6NF-kappa BSevofluranecognitive dysfunctionIL-17AneuroinflammationNF-κB signaling pathwaysevoflurane

Identifiers

PMID35758051
PMCPMC9342424
OpenAlexW4283584285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.