ArticleFrontiers in bioengineering and biotechnology2022
Design, Synthesis, and Application of Carbon Dots With Synergistic Antibacterial Activity.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 52 citations in OpenAlex.
- A critical review on antibacterial mechanisms of carbon dots: a comprehensive approach to combating multidrug resistance.Archives of microbiology · 2026Review
- Review of Antimicrobial Properties of Carbon Nanomaterials.International journal of molecular sciences · 2026Review
- Phenylboronic acid modified AgRSC advances · 2026Article
- Sulfur-Doped Carbon Dots as a Highly Selective and Sensitive Fluorescent Probe for Copper Ion Detection in Biological Systems.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next-Generation Chiral Engineered Biomaterials Applications.Advanced healthcare materials · 2025Review
- Review
- Food-Derived Carbon Dots: Formation, Detection, and Impact on Gut Microbiota.Foods (Basel, Switzerland) · 2025Review
- Antibacterial carbon dots.Materials today. Bio · 2025Review
- Carbon Dots in Photodynamic/Photothermal Antimicrobial Therapy.Nanomaterials (Basel, Switzerland) · 2024Review
- Advances in Engineered Nano-Biosensors for Bacteria Diagnosis and Multidrug Resistance Inhibition.Biosensors · 2024Review
- The Addition of Co into CuO-ZnO Oxides Triggers High Antibacterial Activity and Low Cytotoxicity.Nanomaterials (Basel, Switzerland) · 2023Article
- Recent Progress of Photothermal Therapy Based on Conjugated Nanomaterials in Combating Microbial Infections.Nanomaterials (Basel, Switzerland) · 2023Review
- Trends in Photothermal Nanostructures for Antimicrobial Applications.International journal of molecular sciences · 2023Review
- Heat shock potentiates aminoglycosides against gram-negative bacteria by enhancing antibiotic uptake, protein aggregation, and ROS.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Biogenic Synthesis of Fluorescent Carbon Dots (CDs) and Their Application in Bioimaging of Agricultural Crops.Nanomaterials (Basel, Switzerland) · 2023Article
- Photo-Stimuli-Responsive CuS Nanomaterials as Cutting-Edge Platform Materials for Antibacterial Applications.Pharmaceutics · 2022Review
- Inorganic nanomaterials for intelligent photothermal antibacterial applications.Frontiers in bioengineering and biotechnology · 2022Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diversity of bacteria and their ability to acquire drug resistance lead to many challenges in traditional antibacterial methods. Photothermal therapies that convert light energy into localized physical heat to kill target microorganisms do not induce resistance and provide an alternative for antibacterial treatment. However, many photothermal materials cannot specifically target bacteria, which can lead to thermal damage to normal tissues, thus seriously affecting their biological applications. Here, we designed and synthesized bacteria-affinitive photothermal carbon dots (BAPTCDs) targeting MurD ligase that catalyzes the synthesis of peptidoglycan (PG) in bacteria. BAPTCDs presented specific recognition ability and excellent photothermal properties. BAPTCDs can bind to bacteria very tightly due to their chiral structure and inhibit enzyme activity by competing with D-glutamic acid to bind to MurD ligases, thus inhibiting the synthesis of bacterial walls. It also improves the accuracy of bacteria treatment by laser irradiation. Through the synergy of biochemical and physical effects, the material offers outstanding antibacterial effects and potentially contributes to tackling the spread of antibiotic resistance and facilitation of antibiotic stewardship.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.