Evidence map›Paper›PMID 35757769›Full record

ArticleFrontiers in immunology2022

Antibody-Mediated LILRB2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells to Kill

Vipul K Singh, Arshad Khan, Yitian Xu, Sunny Mai, Licheng Zhang, Abhishek Mishra, Blanca I Restrepo, Ping-Ying Pan, Shu-Hsia Chen, Chinnaswamy Jagannath

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  4. Article
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  8. Here, There, and Everywhere: Myeloid-Derived Suppressor Cells in Immunology.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Vipul K SinghDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Arshad KhanDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Yitian XuCenter for Immunotherapy Research and Cancer Center, Weill Cornell Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Sunny MaiCenter for Immunotherapy Research and Cancer Center, Weill Cornell Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Licheng ZhangCenter for Immunotherapy Research and Cancer Center, Weill Cornell Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Abhishek MishraDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Blanca I RestrepoSchool of Public Health at Brownsville, University of Texas Health Science Center Houston, Brownsville, TX, United States.
Ping-Ying PanCenter for Immunotherapy Research and Cancer Center, Weill Cornell Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Shu-Hsia ChenCenter for Immunotherapy Research and Cancer Center, Weill Cornell Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Chinnaswamy JagannathDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, United States.
Houston Methodist · USWeill Cornell Medicine · USCornell University · USThe University of Texas Rio Grande Valley · US

Funding

A Neonatal Monkey Model of Tuberculosis VaccinationR01AI122070 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GAUDUIN, MARIE-CLAIRE ELISABETH, JAGANNATH, CHINNASWAMY · 2017 to 2021
$4.5M
SigH based attenuated, efficacious Mtb vaccines to protect against lethal TBR01AI138587 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI JAGANNATH, CHINNASWAMY, KAUSHAL, DEEPAK · 2018 to 2022
$4.4M
LILRB modulates tumor microenvironment and promotes tumor progressionR01CA204191 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI CHEN, SHU-HSIA · 2017 to 2022
$2.2M
Role of metabolic Me-macrophages in the pathogenesis of tuberculosis during diabetesR21AI144541 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JAGANNATH, CHINNASWAMY, RESTREPO, BLANCA I · 2020 to 2021
$443k
NCI NIH HHS R01 CA204191NIAID NIH HHS R01 AI122070NIAID NIH HHS R01 AI138587NIAID NIH HHS R21 AI144541
6 · The paper itself

Abstract

Tuberculosis is a leading cause of death in mankind due to infectious agents, and

Indexed as

Membrane GlycoproteinsMycobacterium tuberculosisMyeloid-Derived Suppressor CellsReceptors, ImmunologicTuberculosis, Lymph NodeCytokinesHumansMacrophagesCytokinesLILRB2 protein, humanMembrane GlycoproteinsReceptors, ImmunologicLILRBMDSC (myeloid-derived suppressor cell)monoclonal antibodyMycobacteriumtuberculosis

Identifiers

PMID35757769
PMCPMC9229593
OpenAlexW4281725347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.