Evidence map›Paper›PMID 35757725›Full record

ReviewFrontiers in immunology2022

Thymus Functionality Needs More Than a Few TECs.

Pratibha Bhalla, Dong-Ming Su, Nicolai S C van Oers

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Informed clinical decisions by outfoxing human FOXN1 variants.The Journal of allergy and clinical immunology · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Frontiers in immunology · 2024
    Review
  13. Article
  14. Comprehensive phenotypic analysis of diverse FOXN1 variants.The Journal of allergy and clinical immunology · 2023
    Article
  15. Article
  16. Congenital Athymia: Unmet Needs and Practical Guidance.Therapeutics and clinical risk management · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pratibha BhallaDepartment of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX, United States.
Dong-Ming SuDepartment of Microbiology, Immunology & Genetics, The University of North Texas Health Sciences Center, Fort Worth, TX, United States.
Nicolai S C van OersDepartment of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX, United States.

Funding

Long noncoding RNAs and their contribution to 22q11.2 deletion syndromeR01AI114523 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VAN OERS, NICOLAI STANISLAS CYRILLE · 2015 to 2024
$4.1M
The Functions of Novel FOXN1 Compound Heterozygous Mutations in PIDs PatientsR21AI144140 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VAN OERS, NICOLAI STANISLAS CYRILLE · 2019 to 2020
$446k
NIAID NIH HHS R01 AI114523NIAID NIH HHS R21 AI144140
6 · The paper itself

Abstract

The thymus, a primary lymphoid organ, produces the T cells of the immune system. Originating from the 3

Indexed as

Endothelial CellsThymocytesAdipogenesisAnimalsEpithelial CellsMiceStromal CellsThymus Glandendothelial cellsFOXN1mesenchymal cellsT cell developmentthymusthymus epithelial cellsthymus organoid technologiesthymus regeneration

Identifiers

PMID35757725
PMCPMC9229346

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.