ArticleFrontiers in neuroscience2022
High Fall Risk Associated With Memory Deficit and Brain Lobes Atrophy Among Elderly With Amnestic Mild Cognitive Impairment and Mild Alzheimer's Disease.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Use of Wearable Sensors to Assess Fall Risk in Neurological Disorders: Systematic Review.JMIR mHealth and uHealth · 2025Pooled it
- Advances in gait research related to Alzheimer's disease.Frontiers in neurology · 2025Pooled it
- Genetic evidence does not support causal associations between brain structures and fall risk: evidence from Mendelian randomization.Brain imaging and behavior · 2026Article
- Impact of Reactive Balance Training on a Perturbation Treadmill on Physical Performance in Geriatric Patients:Results of a Single-Center, Assessor Blinded Randomized Controlled Trial.Journal of clinical medicine · 2024Article
- Shifting From Active to Passive Monitoring of Alzheimer Disease: The State of the Research.Journal of the American Heart Association · 2024Review
- Differences in fall-related characteristics across cognitive disorders.Frontiers in aging neuroscience · 2023Review
- Clinical study on gray matter volume reduction, gait disorders, and fall risk in patients with Alzheimer's disease.Frontiers in neurologyArticle
- Impact of cognitive capacity on physical performance in chronic obstructive pulmonary disease patients: A scoping review.Chronic respiratory diseaseArticle
Corrections and comments
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Authors and funding
20 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study aimed to primarily examine the association between memory deficit and increased fall risk, second, explore the underlying neuroanatomical linkage of this association in the elderly with aMCI and mild AD. Methods: In this cross-sectional study, a total of 103 older adults were included (55 cognitively normal, CN; 48 cognitive impairment, CI, elderly with aMCI, and mild AD). Memory was assessed by the Auditory Verbal Learning Test (AVLT). Fall risk was evaluated by the Timed Up and Go (TUG) Test, heel strike angles, and stride speed, which were collected by an inertial-sensor-based wearable instrument (the JiBuEn™ gait analysis system). Brain volumes were full-automatic segmented and quantified using AccuBrain Results: Compared to CN, participants with aMCI and mild AD had poorer cognitive performance ( Conclusion: Our findings suggested that memory deficit was associated with increased fall risk in the elderly with aMCI and mild AD. The association might be mediated by the atrophy of medial temporal, frontal, and parietal lobes. Additionally, increased fall risk, tested by TUG time, heel stride angles, and stride speed, might be objective and convenient kinematics markers for dynamic monitoring of both memory function and fall risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.