Evidence map›Paper›PMID 35757524›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2022

Inhaled Steroids, Sex and Emphysema Index - Clinical Parameters with Impact on the Effectiveness of Valve Implantation in Patients with Severe Emphysema.

Markus Polke, Jonas Brugger, Matthias Rötting, Nilab Polke, Judith Brock, Stefanie Schuler, Ines Richter, Ralf Eberhardt, Felix J F Herth, Daniela Gompelmann

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Pneumo news · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Markus PolkePneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.
Jonas BruggerInstitute for Medical Statistics, Center for Medical Statistics, Informatics and Intelligent Systems, Medical University Vienna, Vienna, Austria.
Matthias RöttingMedizinische Klinik V, Klinikum Fulda, Fulda, Deutschland.
Nilab PolkePneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.
Judith BrockPneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.
Stefanie SchulerPneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.
Ines RichterPneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.
Ralf EberhardtPneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.
Felix J F HerthPneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.ORCID 0000-0002-7638-2506
Daniela GompelmannPneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.
Heidelberg University · DEKlinikum Fulda · DEStatistics Austria · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims and Objectives: Many patients with chronic obstructive lung disease suffer from emphysema. Valve implantation may be a reasonable method in patients presenting advanced emphysema and absent interlobar collateral ventilation (CV). However, other clinical parameters influencing the effectiveness of endoscopic lung volume reduction (ELVR) are not well known. Methods: COPD patients with advanced emphysema who received valve implantation in 2016 were retrospectively analyzed. The following characteristics were collected prior to valve implantation: age, sex, body mass index, presence of allergies, use of inhaled corticosteroids (ICS), lung function parameters, diffusion capacity, 6-minute walk distance (6-MWD), blood gases, COHb, smoking history, and emphysema index (quantitative multi-detector computed tomography). Three months following valve implantation, lung function parameters, diffusion capacity, 6-MWD and blood gases were measured. In this analysis, we evaluated the impact of these variables on an increase in FEV Results: Overall, 77 COPD patients (57% male, mean age 66, mean FEV Conclusion: These findings suggest that ICS, emphysema index and sex are clinical parameters that may be associated with inferior outcome following ELVR. Further studies have to confirm these results to improve patient selection and clinical outcome of ELVR.

Indexed as

EmphysemaPulmonary Disease, Chronic ObstructivePulmonary EmphysemaAgedBronchoscopyFemaleGasesHumansMalePneumonectomyRetrospective StudiesSteroidsTreatment OutcomeGasesSteroidsCOPDemphysemalung volume reductionvalve implantation

Identifiers

PMID35757524
PMCPMC9231414
OpenAlexW4283170216

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.