ReviewFrontiers in endocrinology2022
Growth Hormone Stimulation Testing: To Test or Not to Test? That Is One of the Questions.
Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Variability in the management of healthy short youth following GH stimulation testing.Endocrines · 2026Article
- Real-World Efficacy of Weekly Somatrogon on Growth and Bone Health in Pediatric Growth Hormone Deficiency: A 12-Month Retrospective Cohort StudyJournal of clinical research in pediatric endocrinology · 2026Article
- Growth hormone retesting for idiopathic isolated growth hormone deficiency during and after puberty: a systematic review.Journal of the Endocrine Society · 2026Review
- Beyond GH stimulation tests: genetic heterogeneity and treatment response in children with diagnosed GH deficiency.Journal of the Endocrine Society · 2026Article
- Growth Hormone Withdrawal in Mid-Puberty: No Impact on Near Adult Height in Adolescents With Transient Idiopathic GHD.The Journal of clinical endocrinology and metabolism · 2026Article
- Obesity-Related Changes in Growth Hormone Stimulation Test Performance Under Pediatric Growth Hormone Deficiency.Children (Basel, Switzerland) · 2026Article
- Constructing a precise prediction model for screening growth hormone deficiency in children in a single laboratory setting: using the serum IGF-1-to-age ratio as a promising predictive marker.Translational pediatrics · 2025Article
- Article
- Idiopathic Short Stature in the Genomic Era: Integrating Auxology, Endocrinology, and Emerging Genetic Insights.Children (Basel, Switzerland) · 2025Review
- Auxological parameters associated with the diagnosis of growth hormone deficiency in children with short stature.Pediatric endocrinology, diabetes, and metabolism · 2025Article
- Development and Validation of a Clinical Prediction Model for Growth Hormone Deficiency in Children with Short Stature: A Retrospective Study in China.Journal of multidisciplinary healthcare · 2025Article
- Comparison of growth hormone stimulation tests in prepubertal children with short stature according to response to growth hormone replacement.Annals of pediatric endocrinology & metabolism · 2024Article
- L-DOPA Test in the Diagnosis of Childhood Short Stature: Evaluation of Growth Hormone Peaks Over Time.Endocrinology, diabetes & metabolism · 2024Article
- Acute Effects of Growth Hormone on the Cellular Immunologic Landscape in Pediatric Patients.Cureus · 2024Article
- [Diagnostic significance and considerations of growth hormone stimulation testing and insulin-like growth factor 1 in growth hormone deficiency].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Late-Onset Isolated Growth Hormone Deficiency.JCEM case reports · 2023Article
- Effect of Recombinant Human Growth Hormone Treatment in a Patient with Short Stature Associated with the Ring Chromosome 17 Syndrome.Case reports in pediatrics · 2023Article
- Pituitary hypoplasia and growth hormone deficiency in a patient with Coffin-Siris syndrome and severe short stature: case report and literature review.Archive of clinical cases · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evaluation of children with short stature includes monitoring over a prolonged period to establish a growth pattern as well as the exclusion of chronic medical conditions that affect growth. After a period of monitoring, evaluation, and screening, growth hormone stimulation testing is considered when the diagnosis of growth hormone deficiency (GHD) is entertained. Though flawed, growth hormone stimulation tests remain part of the comprehensive evaluation of growth and are essential for the diagnosis of growth hormone (GH) deficiency. Variables including testing length, growth hormone assay and diagnostic cut off affect results. Beyond the intrinsic issues of testing, results of GH stimulation testing can be influenced by patient characteristics. Various factors including age, gender, puberty, nutritional status and body weight modulate the secretion of GH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.