Evidence map›Paper›PMID 35757382›Full record

ArticleTherapeutic advances in gastroenterology2022

Gastrointestinal manifestations of SARS-CoV-2 infection in an Italian population of hospitalized patients.

Angelo Milano, Konstantinos Efthymakis, Damiano D'Ardes, Marco Tana, Elena Mazzotta, Giulia De Febis, Francesco Laterza, Pierluigi Tarquini, Enrico Marini, Ettore Porreca and 2 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. The "Magnificent Seven" in Oral and Systemic Health against COVID-19.Endocrine, metabolic & immune disorders drug targets · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Angelo MilanoUOSD Endoscopia Digestiva e Gastroenterologia, Ospedale Clinicizzato 'SS Annunziata', ASL2 Abruzzo, Chieti, Italy.
Konstantinos EfthymakisUOSD Endoscopia Digestiva e Gastroenterologia, Ospedale Clinicizzato 'SS Annunziata', ASL2 Abruzzo, Chieti, Italy.ORCID https://orcid.org/0000-0002-9537-6507
Damiano D'ArdesMedicina Generale 1, Ospedale Clinicizzato 'SS Annunziata', ASL2 Abruzzo, Chieti, Italy.
Marco TanaMedicina Generale 2, Ospedale Clinicizzato 'SS Annunziata', ASL2 Abruzzo, Chieti, Italy.
Elena MazzottaMalattie Infettive, Ospedale Civile 'Giuseppe Mazzini', ASL Teramo, Teramo, Italy.
Giulia De FebisMedicina Interna, Ospedale 'San Liberatore', ASL Teramo, Atri, Italy.
Francesco LaterzaUOSD Endoscopia Digestiva e Gastroenterologia, Ospedale Clinicizzato 'SS Annunziata', ASL2 Abruzzo, Chieti, Italy.
Pierluigi TarquiniMalattie Infettive, Ospedale Civile 'Giuseppe Mazzini', ASL Teramo, Teramo, Italy.
Enrico MariniMedicina Interna, Ospedale 'San Liberatore', ASL Teramo, Atri, Italy.
Ettore PorrecaMedicina Generale 2, Ospedale Clinicizzato 'SS Annunziata', ASL2 Abruzzo, Chieti, Italy.
Francesco CipolloneMedicina Generale 1, Ospedale Clinicizzato 'SS Annunziata', ASL2 Abruzzo, Chieti, Italy.
Matteo NeriUOSD Endoscopia Digestiva e Gastroenterologia, Ospedale Clinicizzato 'SS Annunziata', ASL2 Abruzzo, Chieti 66100, Italy.
Ospedale SS. Annunziata · ITUniversity of Chieti-Pescara · ITOspedale San Giuseppe · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus enters the cells Methods: In this cross-sectional study, we included symptomatic patients requiring hospital admission, with a confirmed diagnosis of COVID-19 by nasopharyngeal polymerase chain reaction test, between 18 March and 30 May 2020. Demographic data, symptoms at onset, vital signs, and laboratory tests at admission were recorded. Results: In all, 300 patients were included (57%M, 43%F). GI symptoms were mainly diarrhea (13%), anorexia (4.3%), vomiting (3%), and abdominal pain (2.3%). Overall, males were younger (68 years Conclusion: Our study on an Italian population during the outbreak of the COVID-19 pandemic shows that GI symptoms are part of the spectrum of the SARS-CoV-2 infection and could be the only manifestations at disease onset. Although patients with GI symptoms were associated with faster hospital admission and liver involvement, prognosis was not affected.

Indexed as

GI symptomsSARS-CoV-2

Identifiers

PMID35757382
PMCPMC9218448
OpenAlexW4285167650

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.