Evidence map›Paper›PMID 35757164›Full record

ArticleJournal of women's health physical therapy

Pelvic Floor Mobility measured by Transperineal Ultrasound Imaging in Women with and without Urgency and Frequency Predominant Lower Urinary Tract Symptoms.

Stefanie N Foster, Theresa M Spitznagle, Lori J Tuttle, Jerry L Lowder, Siobhan Sutcliffe, Karen Steger-May, Chiara Ghetti, Jinli Wang, Taylor Burlis, Melanie R Meister and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of women's health physical therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Stefanie N FosterProgram in Physical Therapy, Washington University in St. Louis, St Louis, MO.
Theresa M SpitznagleProgram in Physical Therapy, Washington University in St. Louis, St Louis, MO.
Lori J TuttleDoctor of Physical Therapy Program, San Diego State University, San Diego, CA.
Jerry L LowderDepartment Obstetrics and Gynecology, Washington University in St. Louis, St Louis, MO.
Siobhan SutcliffeDepartment of Surgery, Washington University in St. Louis, St Louis, MO.
Karen Steger-MayDivision of Biostatistics, Washington University in St. Louis, St Louis, MO.
Chiara GhettiDepartment Obstetrics and Gynecology, Washington University in St. Louis, St Louis, MO.
Jinli WangDivision of Biostatistics, Washington University in St. Louis, St Louis, MO.
Taylor BurlisProgram in Physical Therapy, Washington University in St. Louis, St Louis, MO.
Melanie R MeisterDepartment Obstetrics and Gynecology, Washington University in St. Louis, St Louis, MO.
Michael J MuellerProgram in Physical Therapy, Washington University in St. Louis, St Louis, MO.
Marcie Harris-HayesProgram in Physical Therapy, Washington University in St. Louis, St Louis, MO.
Washington University in St. Louis · USSan Diego State University · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
DOCTORAL TRAINING PROGRAM IN MOVEMENT SCIENCET32HD007434 · NICHD · WASHINGTON UNIVERSITY · PI Michael D Harris, Catherine Lang · 1993 to 2026
$4.2M
NCATS NIH HHS UL1 TR002345NICHD NIH HHS T32 HD007434
6 · The paper itself

Abstract

Background: Women with urgency/frequency predominant lower urinary tract symptoms (UF-LUTS) may have elevated pelvic floor muscle (PFM) position at rest and limited mobility with PFM contraction and bearing down, but this has not been quantified. Objectives: To compare PFM position and mobility using transperineal ultrasound (TPUS) at rest, maximal PFM contraction (perineal elevation), and bearing down (perineal descent) in women with and without UF-LUTS. We hypothesized that women with UF-LUTS would demonstrate elevated resting position and decreased excursion of pelvic landmarks during contraction and bearing down as compared to women without UF-LUTS. Study Design: Case-control study. Methods: Women with UF-LUTS were matched 1:1 on age, body mass index and vaginal parity to women without UF-LUTS. TPUS videos were obtained during 3 conditions: rest, PFM contraction, and bearing down. Levator plate angle (LPA) and puborectalis length (PR length), were measured for each condition. Paired t-tests or Wilcoxon signed rank tests compared LPA and PR length between cases and controls. Results: 21 case-control pairs (42 women): Women with UF-LUTS demonstrated greater LPA at rest (66.8 ± 13.2 degrees vs 54.9 ± 9.8 degrees; P=0.006), and less PR lengthening from rest to bearing down (0.2 ± 3.1 mm vs 2.1 ± 2.9 mm; P=.03). Conclusion: Women with UF-LUTS demonstrated more elevated (cranioventral) position of the PFM at rest and less PR muscle lengthening with bearing down. These findings highlight the importance of a comprehensive PFM examination and possible treatment for women with UF-LUTS to include PFM position and mobility.

Indexed as

case-control studyFemale Urogenital Diseasespelvic floor musclepuborectalisurinary frequencyurinary urgency

Identifiers

PMID35757164
PMCPMC9216208
OpenAlexW3213424705

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.