Evidence map›Paper›PMID 35757028›Full record

ArticleMaterials today. Bio2022

Development of a three-dimensional blood-brain barrier network with opening capillary structures for drug transport screening assays.

Marie Piantino, Dong-Hee Kang, Tomomi Furihata, Noriyuki Nakatani, Kimiko Kitamura, Yukari Shigemoto-Mogami, Kaoru Sato, Michiya Matsusaki

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Marie PiantinoDepartment of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
Dong-Hee KangDepartment of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
Tomomi FurihataSchool of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Noriyuki NakataniSCREEN Holdings Co.,Ltd. Development Section 2, R&D Department 1, Furukawa-cho, Hazukashi, Fushimi-ku, Kyoto, Japan.
Kimiko KitamuraDivision of Pharmacology, Laboratory of Neuropharmacology, National Institute of Health Sciences (NIHS), Kawasaki, Kanagawa, Japan.
Yukari Shigemoto-MogamiDivision of Pharmacology, Laboratory of Neuropharmacology, National Institute of Health Sciences (NIHS), Kawasaki, Kanagawa, Japan.
Kaoru SatoDivision of Pharmacology, Laboratory of Neuropharmacology, National Institute of Health Sciences (NIHS), Kawasaki, Kanagawa, Japan.
Michiya MatsusakiDepartment of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.
National Institute of Health Sciences · JPThe University of Osaka · JPSCREEN (Japan) · JPTokyo University of Pharmacy and Life Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The blood-brain barrier (BBB), a selective barrier regulating the active and passive transport of solutes in the extracellular fluid of the central nervous system, prevents the delivery of therapeutics for brain disorders. The BBB is composed of brain microvascular endothelial cells (BMEC), pericytes and astrocytes. Current

Indexed as

Blood-brain barrierDrug screeningIn vitro modelPermeabilitytransferrinReceptor

Identifiers

PMID35757028
PMCPMC9214798
OpenAlexW4282935668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.