Evidence map›Paper›PMID 35756912›Full record

ReviewJAAD international2022

"COVID toes": A true viral phenomenon or a diagnosis without a leg to stand on?

Jia C Gao, Alisen Huang, Ankuri Desai, Bijan Safai, Shoshana Marmon

Abstract readReview
In one paragraph

Review in JAAD international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jia C GaoDepartment of Dermatology, New York Medical College, Valhalla, New York.
Alisen HuangDepartment of Dermatology, State University of New York Downstate Health Sciences University, Brooklyn, New York.
Ankuri DesaiDepartment of Dermatology, State University of New York Downstate Health Sciences University, Brooklyn, New York.
Bijan SafaiDepartment of Dermatology, New York Medical College, Valhalla, New York.
Shoshana MarmonDepartment of Dermatology, New York Medical College, Valhalla, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

"COVID toes" is the colloquial name of chilblain-like lesions thought to be a sequela of COVID-19 infection. Over two years and approximately 300 publications later, this association remains controversial. Here, we summarize key clinical, serological, biological, histological, and immunological evidence that supports and rejects this relationship and discuss alternate theories underlying the pathogenesis of chilblain-like lesions.

Indexed as

acral lesionsacro-ischemiaCBLL, chilblain-like lesionchilblain-like lesions (CBLL)chilblainscoronavirusCOVID-19COVID toescutaneous vasculitisEBV, Epstein-Barr virusEpstein-Barr virus (EBV)factor V Leidenhumoral immunityIFN, interferonIg, immunoglobulininfectioninterferon (IFN)lipoprotein Apandemicperniopostacute sequelae of COVID-19 (PASC)pseudo-chilblainsRT-PCR, reverse transcriptase polymerase chain reactionskin of colorvaccinevirus

Identifiers

PMID35756912
PMCPMC9213024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.