ReviewFrontiers in pain research (Lausanne, Switzerland)2022
The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care.
Review in Frontiers in pain research (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of adverse childhood experiences on analgesia-related outcomes: a systematic review.British journal of anaesthesia · 2025Pooled it
- Pooled it
- Adverse childhood experience is associated with an increased risk of reporting chronic pain in adulthood: a stystematic review and meta-analysis.European journal of psychotraumatology · 2023Pooled it
- Article
- Childhood trauma history and response to behavioral treatments for chronic low back pain.Regional anesthesia and pain medicine · 2026Article
- Cumulative adulthood trauma exposures and pain outcomes among older adults.British journal of pain · 2026Article
- Nurses' competencies, barriers, and experience in trauma-informed care: a cross-sectional study.BMC nursing · 2026Article
- The impact of adverse childhood experiences on cognitive behavioral interventions for chronic pain.Journal of behavioral medicine · 2026Article
- Article
- Childhood maltreatment, trauma, and pain: trauma-related symptoms as mediators in a high-risk group.Pain reports · 2026Article
- Impact of adverse childhood experiences on health-related quality of life in Australian women with endometriosis: a population-based cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Neuroinflammation and Pediatric Chronic Pain - A Review.Current pain and headache reports · 2026Review
- From Trauma to Suicidal Ideation in a Spanish Chronic Pain Population: Cognitive Mediation in the Genesis of Psychological Suffering.Journal of clinical medicine · 2026Article
- Prevalence, severity and correlates of dysmenorrhea among postpartum women in Western Kenya: A cross-sectional study.PLOS global public health · 2026Article
- Associations between childhood adverse experiences and medication adherence in asthma patients: a dual variable-centered and person-centered analysis of attachment security and mentalization.Frontiers in psychiatry · 2026Article
- Women's real-time pain and stress during medical abortion: An ecological momentary assessment study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Long Exhalations as Complementary Treatment for Chronic Pain: A Pilot Study.Journal of clinical medicine · 2025Article
- Autonomic Dysregulation Mediates the Association Between Childhood Trauma and Pain Severity: Evidence from a Mediation Model.Healthcare (Basel, Switzerland) · 2025Article
- Chronic orofacial pain and psychological distress: findings from a multidisciplinary university clinic.Journal of oral & facial pain and headache · 2025Article
- Relationship between adverse childhood experiences and musculoskeletal pain: the mediating effect of depressive symptoms.BMC psychology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adverse childhood experiences (ACEs) increase the likelihood of reduced physical and psychological health in adulthood. Though understanding and psychological management of traumatic experiences is growing, the empirical exploration of ACEs and physical clinical outcomes remains under-represented and under-explored. This topical review aimed to highlight the role of ACEs in the experience of chronic pain, pain management services and clinical decision making by: (1) providing an overview of the relationship between ACEs and chronic pain; (2) identifying biopsychosocial mechanisms through which ACEs may increase risk of persistent pain; (3) highlighting the impact of ACEs on patient adherence and completion of pain management treatment; and (4) providing practical clinical implications for pain management. Review findings demonstrated that in chronic pain, ACEs are associated with increased pain complications, pain catastrophizing and depression and the combination of these factors further heightens the risk of early treatment attrition. The pervasive detrimental impacts of the COVID-19 pandemic on ACEs and their cyclical effects on pain are discussed in the context of psychological decline during long treatment waitlists. The review highlights how people with pain can be further supported in pain services by maintaining trauma-informed practices and acknowledging the impact of ACEs on chronic pain and detrimental health outcomes. Clinicians who are ACE-informed have the potential to minimize the negative influence of ACEs on treatment outcomes, ultimately optimizing the impact of pain management services.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.