Evidence map›Paper›PMID 35756884›Full record

ArticleIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society

Coherent anti-Stokes Raman scattering microspectroscopy: an emerging technique for non-invasive optical assessment of a local bio-nano-environment.

Anton D Shutov, Joseph T Harrington, Hanlin Zhu, Da-Wei Wang, Delong Zhang, Vladislav V Yakovlev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anton D ShutovTexas A&M University. He is currently with 10x Genomics, Inc., 6230 Stoneridge Mall Road, Pleasanton, CA 94888 USA.
Joseph T HarringtonDepartment of Physics and Astronomy, Texas A&M University, College Station, TX 77843 USA.
Hanlin ZhuDepartment of Physics, Zhejiang University, Hangzhou, Zhejiang 310027 China.
Da-Wei WangInterdisciplinary Center of Quantum Information and Zhejiang Province Key Laboratory of Quantum Technology and Device, Department of Physics and State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310027 China.
Delong ZhangInterdisciplinary Center of Quantum Information and Zhejiang Province Key Laboratory of Quantum Technology and Device, Department of Physics and State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou, Zhejiang 310027 China.
Vladislav V YakovlevDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843 USA.

Funding

Brillouin Microscope for Biomedical ResearchR01GM127696 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI YAKOVLEV, VLADISLAV V. · 2018 to 2021
$1.1M
Sensing local nano-environment with coherent Raman microspectroscopyR21GM142107 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI YAKOVLEV, VLADISLAV V. · 2021 to 2022
$399k
NIGMS NIH HHS R01 GM127696NIGMS NIH HHS R21 GM142107
6 · The paper itself

Abstract

Raman spectroscopy provides a non-invasive, chemically-specific optical imaging of biological objects without relying on endogenous labels. Nonlinear Raman spectroscopy allows non-invasive imaging at much faster speed with an improved spatial resolution and axial sectioning capability. In this report we propose a novel use of nonlinear Raman spectroscopy as a sensor of local nano-environment. Time-resolved coherent anti-Stokes Raman spectrograms are found to be sensitive to small variations of local structural changes, which are not normally observed using conventional Raman spectroscopy.

Indexed as

Biomedical imagingNonlinear opticsRaman scatteringTime-domain analysis

Identifiers

PMID35756884
PMCPMC9232098

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.