Evidence map›Paper›PMID 35756878›Full record

ArticleProceedings. Mathematical, physical, and engineering sciences2022

Stability selection enables robust learning of differential equations from limited noisy data.

Suryanarayana Maddu, Bevan L Cheeseman, Ivo F Sbalzarini, Christian L Müller

Open access · greenAbstract read
In one paragraph

Article in Proceedings. Mathematical, physical, and engineering sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Nonlinear memory in cell-division dynamics across species.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Integrated path stability selection.Journal of the American Statistical Association · 2025
    Article
  3. Article
  4. Article
  5. Learning hydrodynamic equations for active matter from particle simulations and experiments.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Stability selection enables robust learning of differential equations from limited noisy data.Proceedings. Mathematical, physical, and engineering sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Suryanarayana MadduFaculty of Computer Science, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0003-2702-4427
Bevan L CheesemanFaculty of Computer Science, Technische Universität Dresden, Dresden, Germany.
Ivo F SbalzariniFaculty of Computer Science, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0003-4414-4340
Christian L MüllerCenter for Computational Mathematics, Flatiron Institute, New York, NY, USA.ORCID 0000-0002-3821-7083
Center for Systems Biology Dresden · DEFlatiron Health (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a statistical learning framework for robust identification of differential equations from noisy spatio-temporal data. We address two issues that have so far limited the application of such methods, namely their robustness against noise and the need for manual parameter tuning, by proposing stability-based model selection to determine the level of regularization required for reproducible inference. This avoids manual parameter tuning and improves robustness against noise in the data. Our stability selection approach, termed PDE-STRIDE, can be combined with any sparsity-promoting regression method and provides an interpretable criterion for model component importance. We show that the particular combination of stability selection with the iterative hard-thresholding algorithm from compressed sensing provides a fast and robust framework for equation inference that outperforms previous approaches with respect to accuracy, amount of data required, and robustness. We illustrate the performance of PDE-STRIDE on a range of simulated benchmark problems, and we demonstrate the applicability of PDE-STRIDE on real-world data by considering purely data-driven inference of the protein interaction network for embryonic polarization in

Indexed as

differential equationsmachine learningPAR proteinssparse regressionstability selectionstatistical learning theory

Identifiers

PMID35756878
PMCPMC9199075
OpenAlexW4282913006

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.