Evidence map›Paper›PMID 35756812›Full record

ArticleJournal of dental sciences2022

Novel low-shrinkage-stress bioactive nanocomposite with anti-biofilm and remineralization capabilities to inhibit caries.

Hanan Filemban, Ghalia Bhadila, Xiaohong Wang, Mary Ann S Melo, Thomas W Oates, Michael D Weir, Jirun Sun, Hockin H K Xu

Open access · goldAbstract read
In one paragraph

Article in Journal of dental sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  9. Novel antibacterial low-shrinkage-stress resin-based cement.Dental materials : official publication of the Academy of Dental Materials · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hanan FilembanPh.D. Program in Dental Biomedical Sciences, Biomaterials and Tissue Engineering Division, University of Maryland School of Dentistry, Baltimore, USA.
Ghalia BhadilaDepartment of Pediatric Dentistry, King AbdulAziz University, Jeddah, Saudi Arabia.
Xiaohong WangAmerican Dental Association Science and Research Institute, LLC., Gaithersburg, USA.
Mary Ann S MeloDivision of Operative Dentistry, Department of General Dentistry, University of Maryland School of Dentistry, Baltimore, USA.
Thomas W OatesDepartment of Advanced Oral Sciences and Therapeutics, University of Maryland School of Dentistry, Baltimore, USA.
Michael D WeirDepartment of Advanced Oral Sciences and Therapeutics, University of Maryland School of Dentistry, Baltimore, USA.
Jirun SunThe Forsyth Institute, Harvard School of Dental Medicine Affiliate, Cambridge, USA.
Hockin H K XuDepartment of Advanced Oral Sciences and Therapeutics, University of Maryland School of Dentistry, Baltimore, USA.
University of Maryland, Baltimore · USAmerican Dental Association · USKing Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: A common reason for dental composite restoration failure is recurrent caries at the margins. Our objectives were to: (1) develop a novel low-shrinkage-stress, antibacterial and remineralizing resin composite; (2) evaluate the effects of dimethylaminohexadecyl methacrylate (DMAHDM) on mechanical properties, biofilm inhibition, calcium (Ca) and phosphate (P) ion release, degree of conversion, and shrinkage stress on the new low-shrinkage-stress resin composite for the first time. Material and methods: The resin consisted of urethane dimethacrylate (UDMA) and triethylene glycol divinylbenzyl ether (TEG-DVBE) with high resistance to salivary hydrolytic degradation. Composites were made with 0%-8% of DMAHDM for antibacterial activity, and 20% of nanoparticles of amorphous calcium phosphate (NACP) for remineralization. Mechanical properties and Results: Adding 2-5% DMAHDM and 20% NACP into the low-shrinkage-stress composite did not compromise the mechanical properties (p > 0.05). The incorporation of DMAHDM greatly reduced Conclusion: The bioactive low-shrinkage-stress composite reduced the polymerization shrinkage stress, without compromising other properties. Increasing the DMAHDM content increased the antibacterial effect in a dose-dependent manner.

Indexed as

Anti-biofilmBioactiveCalcium phosphate nanoparticlesDental nanocompositeLow shrinkage stressSecondary caries

Identifiers

PMID35756812
PMCPMC9201927
OpenAlexW3207586871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.