Evidence map›Paper›PMID 35756729›Full record

ArticleClinical kidney journal2022

Epidemiology of native kidney disease in Flanders: results from the FCGG kidney biopsy registry.

Wim Laurens, Dries Deleersnijder, Amélie Dendooven, Evelyne Lerut, An S De Vriese, Tom Dejagere, Mark Helbert, Rachel Hellemans, Priyanka Koshy, Bart Maes and 8 more

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  11. Lupus Nephritis from Pathogenesis to New Therapies: An Update.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Wim LaurensDepartment of Nephrology and Dialysis, AZ Nikolaas Hospital, Sint-Niklaas, Belgium.
Dries DeleersnijderDepartment of Microbiology, Immunology and Transplantation, Laboratory of Molecular Immunology, Rega Institute, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-8285-6624
Amélie DendoovenDivision of Pathology, University Hospital Ghent, Ghent, Belgium.ORCID https://orcid.org/0000-0002-9900-7952
Evelyne LerutDepartment of Imaging and Pathology, KU Leuven, Leuven, Belgium.
An S De VrieseDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.ORCID https://orcid.org/0000-0002-9596-8529
Tom DejagereDepartment of Nephrology, Jessa Hospital, Hasselt, Belgium.
Mark HelbertDepartment of Nephrology, ZNA Middelheim Hospital, Antwerp, Belgium.
Rachel HellemansLaboratory of Experimental Medicine and Pediatrics, University of Antwerp, Wilrijk, Belgium.
Priyanka KoshyDepartment of Pathology, University Hospitals Leuven, Leuven, Belgium.
Bart MaesDepartment of Nephrology, AZ Delta, Roeselare, Belgium.
Lissa PipeleersDepartment of Nephrology, University Hospital Brussels, Brussels, Belgium.
Amaryllis H Van CraenenbroeckDivision of Nephrology, University Hospitals Leuven, Leuven, Belgium.
Steven Van LaeckeRenal Division, Department of Internal Medicine, Ghent University Hospital, Ghent, Belgium.
Johan Vande WalleDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.ORCID https://orcid.org/0000-0001-9700-5358
Marie M CoutteneyeLaboratory of Experimental Medicine and Pediatrics, University of Antwerp, Wilrijk, Belgium.
Johan De MeesterDepartment of Nephrology and Dialysis, AZ Nikolaas Hospital, Sint-Niklaas, Belgium.
Ben SprangersDepartment of Microbiology, Immunology and Transplantation, Laboratory of Molecular Immunology, Rega Institute, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0003-1314-9675
FCGG collaborative group
Ghent University Hospital · BEKU Leuven · BEUniversity of Antwerp · BEAZ Delta · BERega Institute for Medical Research · BEVlaamse Vereniging voor Obstetrie en Gynaecolo · BEZNA Middelheim Hospital · BEJessa Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Flemish Collaborative Glomerulonephritis Group (FCGG) registry is the first population-based native kidney biopsy registry in Flanders, Belgium. In this first analysis, we report on patient demographics, frequency distribution and incidence rate of biopsied kidney disease in adults in Flanders. Methods: From January 2017 to December 2019, a total of 2054 adult first native kidney biopsies were included. A 'double diagnostic coding' strategy was used, in which every biopsy sample received a histopathological and final clinical diagnosis. Frequency distribution and incidence rate of both diagnoses were reported and compared with other European registries. Results: The median age at biopsy was 61.1 years (interquartile range, 46.1-71.7); male patients were more prevalent (62.1%) and biopsy incidence rate was 129.3 per million persons per year. Immunoglobulin A nephropathy was the most frequently diagnosed kidney disease (355 biopsies, 17.3% of total) with a similar frequency as in previously published European registries. The frequency of tubulointerstitial nephritis (220 biopsies, 10.7%) and diabetic kidney disease (154 biopsies, 7.5%) was remarkably higher, which may be attributed to changes in disease incidence as well as biopsy practices. Discordances between histopathological and final clinical diagnoses were noted and indicate areas for improvement in diagnostic coding systems. Conclusions: The FCGG registry, with its 'double diagnostic coding' strategy, provides useful population-based epidemiological data on a large Western European population and allows subgroup selection for future research.

Indexed as

biopsyepidemiologyfrequencyincidencenative kidneyobservationalpathologyregistry

Identifiers

PMID35756729
PMCPMC9217646
OpenAlexW4210667345

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.