Evidence map›Paper›PMID 35756683›Full record

ArticleFrontiers in oncology2022

Development of Approaches and Metrics to Measure the Impact and Improve the Clinical Outcomes of Patients With Frailty in the Era of COVID-19. The COMETA Italian Protocol.

Nicola Silvestris, Valeria Belleudi, Antonio Addis, Fulvia Pimpinelli, Aldo Morrone, Salvatore Sciacchitano, Rita Mancini, Vito Michele Garrisi, Massimo Costantini, Gennaro Ciliberto and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05792891 (Development of Approaches and Metrics to Measure the Impact and Improve the Clinical Outcomes of Patients With Frailty in the Era of COVID-19.), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05792891 completednot on this map

Development of Approaches and Metrics to Measure the Impact and Improve the Clinical Outcomes of Patients With Frailty in the Era of COVID-19.

TypeobservationalSponsorRegina Elena Cancer InstituteRan2020 to 2022Enrolled150ConditionsFrailty, Oncology, Immune DeficiencyArmsCollecting biological material from frail patients, with or without COVID-19
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Nicola SilvestrisIstituto Tumori "Giovanni Paolo II" of Bari, IRCCS, Bari, Italy.
Valeria BelleudiDepartment of Epidemiology, Lazio Regional Health Service, Roma, Italy.
Antonio AddisDepartment of Epidemiology, Lazio Regional Health Service, Roma, Italy.
Fulvia PimpinelliSan Gallicano Dermatological Institute, IRCCS, Roma, Italy.
Aldo MorroneSan Gallicano Dermatological Institute, IRCCS, Roma, Italy.
Salvatore SciacchitanoAzienda Ospedaliera Universitaria Sant'Andrea, Sapienza University, Roma, Italy.
Rita ManciniAzienda Ospedaliera Universitaria Sant'Andrea, Sapienza University, Roma, Italy.
Vito Michele GarrisiIstituto Tumori "Giovanni Paolo II" of Bari, IRCCS, Bari, Italy.
Massimo CostantiniGeriatric Unit, Azienda Unità Sanitaria Locale (AUSL), IRCCS, Reggio Emilia, Italy.
Gennaro CilibertoIRCCS, National Cancer Institute Regina Elena, Roma, Italy.
Vincenza FrisardiGeriatric Unit, Azienda Unità Sanitaria Locale (AUSL), IRCCS, Reggio Emilia, Italy.
Giulia PiaggioIRCCS, National Cancer Institute Regina Elena, Roma, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITAzienda Ospedaliera Sant'Andrea · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITIstituto Tumori Bari · ITSan Gallicano Hospital · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outbreak of the coronavirus 2 disease 2019 (COVID-19) puts an enormous burden on healthcare systems worldwide. This may worsen outcomes in patients with severe chronic diseases such as cancer, autoimmune diseases, and immune deficiencies. In this critical situation, only a few available data exist, which do not allow us to provide practical guides for the treatment of oncological or immunocompromised patients. Therefore, a further step forward is needed, addressing the specific needs and demands of frail patients in the pandemic era. Here we aim to present a protocol of a study approved by an ethical committee named "CO.M.E.TA". CO.M.E.TA protocol is a network project involving six Italian institutions and its goals are: i) to measure and compare the impact of the pandemic on the access of cancer and immunocompromised patients to therapies in three Italian regions; ii) to assess how reorganizational measures put in place in these different institutions have impacted specific metrics of performance; iii) to establish a COVID-19 Biobank of biological samples from SARS-CoV-2 infected patients to be used to study immunological alterations in patients with immune frailty.

Indexed as

blood biobankcancer screeningsimmune responsepandemicSARS-CoV-2tracking fragile patients

Identifiers

PMID35756683
PMCPMC9215159
OpenAlexW4281761915

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.