Evidence map›Paper›PMID 35756410›Full record

ArticleComputational and mathematical methods in medicine2022

Clinical Study of Intravitreal Injection of Anti-VEGF Drugs Combined with Triamcinolone Acetonide in the Treatment of Coats Disease.

ShaoFeng Wu, Jing Fang, Fang Yu, Fang Han, Jun Xiao

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

ShaoFeng Wu *Department of Ophthalmology, Huangmei People's Hospital, 137 Wuzu Dadao, Huangmei Town, Huangmei County, Huanggang City, Hubei Province 435500, China.ORCID https://orcid.org/0000-0002-0864-3751
Jing Fang *Anesthesiology Department, Caidian District People's Hospital of Wuhan, No. 111 Chenggong Avenue, Caidian District, Wuhan City, Hubei Province 430100, China.ORCID https://orcid.org/0000-0001-7631-7002
Fang YuShenzhen Hospital, University of Chinese Academy of Sciences (Guangming) (Ophthalmology), 39 Huaxia Road, Guangming Street, Guangming District, Shenzhen City, Guangdong Province 518107, China.ORCID https://orcid.org/0000-0002-6177-796X
Fang HanXiangyang Integrated Traditional Chinese and Western Medicine Hospital/Ophthalmology, No. 16, Dongfeng Automobile Avenue, High Tech Zone, Xiangyang City, Hubei Province 411000, China.ORCID https://orcid.org/0000-0002-4742-8843
Jun XiaoEastern Hubei Medical Group City Maternal and Child Health Hospital Ophthalmology, 9 Guilin South Road, Xialu District, Huangshi City, Hubei Province 435000, China.ORCID https://orcid.org/0000-0002-1906-6208
Hubei Provincial Women and Children's Hospital · CNMeizhou City People's Hospital · CNUniversity of Chinese Academy of Sciences · CNXiangyang Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the clinical study of intravitreal injection of anti-VEGF drugs combined with intravitreal injection of tretinoin for the treatment of Coats disease. Methods: The medical records of 90 patients (120 eyes) with Coats disease admitted to our hospital from April 2010 to June 2021 were selected as retrospective study subjects and divided into control and treatment groups according to the numerical table method. There were 45 cases and 60 eyes in each group. Among them, intravitreal tretinoin drug was injected into the control group, and anti-VEGF drug was injected into the vitreous sclera of the treatment group on the basis of the control group. Results: Before treatment, the differences in visual acuity changes between the two groups were not statistically significant ( Conclusion: Intravitreal injection of anti-VEGF drugs combined with tretinoin injection can significantly improve the clinical efficacy of patients with Coats disease and improve visual acuity and central retinal thickness, which has certain reference value for the clinical treatment of Coats disease.

Indexed as

Retinal TelangiectasisTriamcinolone AcetonideAngiogenesis InhibitorsHumansIntravitreal InjectionsRetrospective StudiesTreatment OutcomeTretinoinAngiogenesis InhibitorsTretinoinTriamcinolone Acetonide

Identifiers

PMID35756410
PMCPMC9232298
OpenAlexW4283072662

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.