Evidence map›Paper›PMID 35756016›Full record

ArticleFrontiers in microbiology2022

Functional Characterization of the Thrombospondin-Related Paralogous Proteins Rhoptry Discharge Factors 1 and 2 Unveils Phenotypic Plasticity in

Alessia Possenti, Manlio Di Cristina, Chiara Nicastro, Matteo Lunghi, Valeria Messina, Federica Piro, Lorenzo Tramontana, Simona Cherchi, Mario Falchi, Lucia Bertuccini and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. AmSphere · 2024
    Article
  6. The Immunoprotective Effect of ROP27 Protein ofAnimals : an open access journal from MDPI · 2023
    Article
  7. Comparative Proteomic Analysis ofInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Alessia PossentiDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Manlio Di CristinaDepartment of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.
Chiara NicastroDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Matteo LunghiDepartment of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.
Valeria MessinaDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Federica PiroDepartment of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.
Lorenzo TramontanaDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Simona CherchiDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Mario FalchiNational AIDS Center, Istituto Superiore di Sanità, Rome, Italy.
Lucia BertucciniCore Facilities, Istituto Superiore di Sanità, Rome, Italy.
Furio SpanoDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Istituto Superiore di Sanità · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To gain access to the intracellular cytoplasmic niche essential for their growth and replication, apicomplexan parasites such as

Indexed as

gene redundancyhost cell invasionrhoptry exocytosisthrombospondin-related proteinsToxoplasma gondii

Identifiers

PMID35756016
PMCPMC9218915
OpenAlexW4281617334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.