ReviewAustralian prescriber2022
Hormonal contraception and mood disorders.
Review in Australian prescriber, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of combined oral contraceptives and progestin-only pills on psychological and sexual well-being of women with endometriosis: A systematic review.Acta obstetricia et gynecologica Scandinavica · 2026Pooled it
- Effects of Oral Contraceptive Pills on Brain Networks: A Conceptual Replication and Extension.Human brain mapping · 2025Trial
- Vitamin D and wound healing: Assessing skin barrier function and implications for chloasma treatment.International wound journal · 2024Trial
- Association between combined oral contraceptive pills and depression in women with polyendocrine metabolic ovarian syndrome (formerly polycystic ovary syndrome): a comparative cross-sectional study.BMC women's health · 2026Article
- Contraceptive use among sexually active school-going adolescents in three Southeast Asian Countries: a cross-sectional study.Korean journal of family medicine · 2026Article
- Poor mood after oral contraceptive use is associated with increased vulnerability to peripartum depression, premenstrual dysphoric disorder, and higher genetic risk for depression.Archives of women's mental health · 2026Article
- Do sex and gender matter in the pharmacological treatment of depression?Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Hormonal contraceptives impair psychomotor vigilance task performance under sleep deprivation with stress induction.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Sperm-disrupting activity of a root bark fraction ofFrontiers in pharmacology · 2026Article
- Hormonal contraception and mental health: a narrative review of screening, monitoring, and patient-centered care for family physicians.Frontiers in psychiatry · 2026Review
- Natural relief for premenstrual syndrome (PMS): a double-blind clinical trial on the efficacy and safety of PMSoff.Journal of pharmaceutical health care and sciences · 2025Article
- Oral contraceptive use and its sociocultural determinants in Iranian women: a secondary cross-sectional analysis from the PARS cohort study.Contraception and reproductive medicine · 2025Article
- Contraception and Mood Effects-Psychopharmacology bulletin · 2025Article
- Extensive modulation of the circulating blood proteome by hormonal contraceptive use across two population studies.Communications medicine · 2025Article
- The impact of ovulation-suppressing contraceptives on behavioral and functional difficulties in borderline personality disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- The link between sex hormones and depression over a woman's lifespan (Review).Biomedical reports · 2025Review
- Hormonal Contraceptive Use and Affective Disorders: An Updated Review.Open access journal of contraception · 2025Review
- A comparison of the knowledge of hormonal contraception between women living in urban and rural areas of Poland.PloS one · 2025Article
- Using estrogen and progesterone to treat premenstrual dysphoric disorder, postnatal depression and menopausal depression.Frontiers in pharmacology · 2025Review
- Estrogen and psychosis - a review and future directions.Archives of women's mental health · 2024Review
Corrections and comments
- Commented on by
- Commented on by
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hormonal contraception is known to precipitate or perpetuate depression in some patients. The link between oral contraceptive pills and depression relates to the amount and type of progestogen contained in these pills. Many of the older oral contraceptive pills, which contain ethinylestradiol, are linked to severe mood problems. Newer oral contraceptive pills containing physiological forms of oestrogen may be better tolerated with a purported weaker link to mood problems. Clinicians should consider the temporal relationship between the use of hormonal contraception and development of new or worsened depression or mood changes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.