Evidence map›Paper›PMID 35755914›Full record

ReviewSleep science (Sao Paulo, Brazil)

Sleep deprivation: a risk for epileptic seizures.

Jason Tyler Dell'Aquila, Varun Soti

Open access · diamondAbstract readReview
In one paragraph

Review in Sleep science (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
  2. Article
  3. Circadian Rhythms Time Seizure Severity inJournal of biological rhythms · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Exploring sleep challenges in CDKL5 Deficiency Disorder.Journal of neurodevelopmental disorders · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Epilepsy grand challenge 2025.Frontiers in neurology · 2025
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jason Tyler Dell'AquilaLake Erie College of Osteopathic Medicine, Osteopathic Medical Student, 2nd year year - Elmira - New York - United States.
Varun SotiLake Erie College of Osteopathic Medicine, Assistant Professor of Pharmacology - Elmira - New York - United States.
Lake Erie College of Osteopathic Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a well-documented correlation between epilepsy and sleep deprivation. For decades, preclinical and clinical studies have shown that sleep deprivation can lead to an increased risk of epileptic seizures. Additionally, sleep deprivation has been used clinically as a diagnostic tool for epilepsy by triggering epileptiform activity. However, an underlying mechanism for this relationship is yet to be confirmed. Interestingly, a decrease in gamma-aminobutyric acid (GABA)-mediated tonic inhibition has been shown in both epilepsy and sleep deprivation. This review focuses on the role of sleep deprivation in the induction of epileptic seizures and the possible role of reduced GABA receptor expression in the sleep-deprived state.

Indexed as

EpilepsyGamma-Aminobutyric AcidPhysiologySleep

Identifiers

PMID35755914
PMCPMC9210558
OpenAlexW4283661439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.