ArticleFrontiers in plant science2022
Snailase: A Promising Tool for the Enzymatic Hydrolysis of Flavonoid Glycosides From Plant Extracts.
Article in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Enhanced Antioxidant and Anti-Inflammatory Activities ofAntioxidants (Basel, Switzerland) · 2025Article
- Enzymatic Deglycosylation and Lipophilization of Soy Glycosides into Value-Added Compounds for Food and Cosmetic Applications.ACS omega · 2025Article
- From Random Perturbation to Precise Targeting: A Comprehensive Review of Methods for Studying Gene Function inJournal of fungi (Basel, Switzerland) · 2024Review
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Abstract
Plants typically contain a broad spectrum of flavonoids in varying concentrations. As a rule, several flavonoid classes occur in parallel, and, even for a single flavonoid, divergent glycosylation patterns are frequently observed, many of which are not commercially available. This can be challenging in studies in which the distribution between flavonoid classes, or features that are not affected by glycosylation patterns, are adressed. In addition, hydrolysis simplifies the quantification process by reducing peak interferences and improving the peak intensity due to the accumulation of the respective aglycone. Effective removal of glycose moieties can also be relevant for technological applications of flavonoid aglycones. Herein, we present a fast and reliable method for the enzymatic hydrolysis glycosides from plant extracts using the commercial enzyme mix snailase, which provided the highest aglycone yields across all investigated flavonoids (aurones: leptosidin, maritimetin, sulfuretin; chalcones: butein, lanceoletin, okanin, phloretin; dihydroflavonols: dihydrokaempferol; flavanones: eriodictyol, hesperetin; flavones: acacetin, apigenin, diosmetin, luteolin; flavonols: isorhamnetin, kaempferol, myricetin, quercetin; isoflavones: biochanin A, formononetin, genistein) from methanolic extracts of nine plants (
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