Evidence map›Paper›PMID 35755542›Full record

ArticleCureus2022

Drug-Induced Gum Overgrowth With Low-Dose Amlodipine: A Case Report.

Sadikshya Bhandari, Shisir Siwakoti, Shreeya Shrestha, Kushal Gautam, Samikshya Bhandari

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sadikshya BhandariInternal Medicine, Dhulikhel Hospital, Dhulikhel, NPL.
Shisir SiwakotiInternal Medicine, Dhulikhel Hospital, Dhulikhel, NPL.
Shreeya ShresthaInternal Medicine, Dhulikhel Hospital, Dhulikhel, NPL.
Kushal GautamInternal Medicine, Paediatric Research Unit, Patan Academy of Health Sciences, Lalitpur, NPL.
Samikshya BhandariInternal Medicine, Nepal Medical College Teaching Hospital, Kathmandu, NPL.
Dhulikhel Hospital · NPNepal Medical College Teaching Hospital · NPKathmandu Medical College Teaching Hospital · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced gingival overgrowth is an adverse effect of certain drugs, including amlodipine, in genetically susceptible individuals. Although the exact mechanism of gingival hypertrophy remains unclear, a unifying multifactorial hypothesis has been constructed. Gingival hypertrophy causes difficulty in speech and mastication, poor oral hygiene, and poor aesthetic appearance. Here, we present the case of a 49-year-old woman who developed gum hypertrophy following amlodipine use for two years. Maintenance of oral hygiene and substitution of offending agent is commonly the first step in management.

Indexed as

adverse effectsamlodipineantihypertensive drugsdental healthdigogum hypertrophygum overgrowth

Identifiers

PMID35755542
PMCPMC9217670
OpenAlexW4281295457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.