ArticleIJID regions2022
The evaluation of anti-diphtheria toxoid antibodies in healthy population in Kon Tum, Vietnam: a population-based study.
Article in IJID regions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Mapping anti-diphtheria toxin antibody: a systematic review and meta-analysis with multi-level meta-regression.Pathogens and global healthPooled it
- Diphtheria seroprotection among Indonesian children: Community Health Surveys Riskesdas 2007, 2013 and 2018.PloS one · 2026Article
- Article
- Seroprevalence of anti-diphtheria toxoid antibody and implications for vaccination policy in Vietnam's South-central coast: a cross-sectional study.BMC infectious diseases · 2024Article
- Diphtheria and Tetanus Immunity Status among Greek Adults: Results from a Nationwide Seroprevalence Study.Vaccines · 2024Article
- Genetic characterization of diphtheriaIranian journal of microbiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Despite diphtheria immunization are to apply an effective primary immunization in childhood and to maintain immunity throughout life. Cases of diphtheria have been reported in Viet Nam in recent years. The aim of this study was to evaluate the seroprevalence of IgG antibodies to diphtheria toxoid among healthy person population in Kon Tum, Viet Nam. Methods: Blood samples were obtained from 2225 healthy persons aged 2-98 years collected in 2019 and 2020. Samples were tested for diphtheria toxoid antibodies by commercial Anti-Diphtheria Toxoid IgG Enzyme-Linked Immunosorbent Assay (ELISA). Results: An antibody level of <0.01 IU/mL (susceptibility) was found in 802 (36.0%) of the 2225 subjects, 136 (6.1%) had antibody levels of 0.01-0.099 IU/mL (basic protection), and 1287 (57.8%) had antibody levels ≥0.1 IU/mL (full protection). The full protection level increased significantly in persons aged above 60 years with antibody levels of 70.6%. No significant difference in seroprotection prevalence was found according to gender, ethnicity, residence, education and occupation. The results also demonstrated that people with vaccination against diphtheria during past 10 years were found to have a high immunity (83.8%) compared to 54.8% (OR: 4.7; 95%CI: 3.8-6.5) and 60.7% (OR: 3.8; 95%CI: 2.6-5.7) in persons with no and unknown vaccination (p <0.0001). Conclusions: The level of anti-diphtheria toxoid antibodies among children and adults in Kon Tum was low. The high risk of diphtheria outbreaks may occur among individuals lacking basic immunity against diphtheria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.