Evidence map›Paper›PMID 35755459›Full record

ArticleIJID regions2022

Epidemiological and laboratory characteristics of multidrug-resistant tuberculosis patients in Bhutan, 2015-2019.

Lila Adhikari, Sonam Wangchuk, Pavitra Bhujel, Sherab Zangmo, Pema Lhaden, Ugyen Dorji, Karchung Tshering

Abstract read
In one paragraph

Article in IJID regions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lila AdhikariRoyal Centre for Disease Control, Ministry of Health, Bhutan.
Sonam WangchukRoyal Centre for Disease Control, Ministry of Health, Bhutan.
Pavitra BhujelRoyal Centre for Disease Control, Ministry of Health, Bhutan.
Sherab ZangmoRoyal Centre for Disease Control, Ministry of Health, Bhutan.
Pema LhadenRoyal Centre for Disease Control, Ministry of Health, Bhutan.
Ugyen DorjiRoyal Centre for Disease Control, Ministry of Health, Bhutan.
Karchung TsheringRoyal Centre for Disease Control, Ministry of Health, Bhutan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bhutan is no exception to the rising global threat of drug resistance tuberculosis (TB), particularly multidrug-resistant (MDR) TB. Although drug resistance surveillance has been carried out in Bhutan since 2010, limited analysis reports are available. Therefore, we looked at data from 2015-2019 to understand patient characteristics. Method: To obtain data for MDR-TB from the past 5 years, we looked at manual registers and laboratory worksheets for all samples received at National TB Reference Laboratory. Epidemiological factors and laboratory variables were analyzed using descriptive statistics. Result: Among 304 patients with MDR-TB, 85.20% (n=259) are new cases with no previous history of treatment. Those aged 16-25 years from both genders are affected more (46.05%, n=140) than other age groups. The majority (94.62%, n=264) of rifampicin resistance was found in the Conclusion: A high number of MDR-TB cases among new patients and little variation in the resistance band pattern over 5 years could indicate uncontrolled ongoing transmission. Whole-genome sequencing for the samples is required to further understand the epidemiology of the resistance pattern.

Indexed as

line probe assay patternsMultidrug resistancenationwide MDR-TB surveillance

Identifiers

PMID35755459
PMCPMC9216444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.