Evidence map›Paper›PMID 35755451›Full record

ArticleFrontiers in genome editing2022

Impacts of RNA Mobility Signals on Virus Induced Somatic and Germline Gene Editing.

Bliss M Beernink, Ryan R Lappe, Melissa Bredow, Steven A Whitham

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genome editing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Behind (cell) walls.Nature biotechnology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Genetic transformation and genome editing of flax (Frontiers in plant science · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bliss M BeerninkDepartment of Plant Pathology and Microbiology, Iowa State University, Ames, IA, United States.
Ryan R LappeDepartment of Plant Pathology and Microbiology, Iowa State University, Ames, IA, United States.
Melissa BredowDepartment of Plant Pathology and Microbiology, Iowa State University, Ames, IA, United States.
Steven A WhithamDepartment of Plant Pathology and Microbiology, Iowa State University, Ames, IA, United States.
Iowa State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral vectors are being engineered to deliver CRISPR/Cas9 components systemically in plants to induce somatic or heritable site-specific mutations. It is hypothesized that RNA mobility signals facilitate entry of viruses or single guide RNAs (sgRNAs) into the shoot apical meristem where germline mutations can occur. Our objective was to understand the impact of RNA mobility signals on virus-induced somatic and germline gene editing in

Indexed as

barley stripe mosaic virusCRISPR/Cas9foxtail mosaic virusNicotiana benthamianapotato virus Xtobacco rattle virusvirus-induced gene editingZea mays

Identifiers

PMID35755451
PMCPMC9219249
OpenAlexW4281698692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.