Evidence map›Paper›PMID 35755259›Full record

ArticleFrontiers in chemistry2022

Synthesis of Melatonin Derivatives and the Neuroprotective Effects on Parkinson's Disease Models of

Li He, Jing-Jing Du, Jun-Jie Zhou, Meng-Ting Chen, Lu Luo, Bao-Qiong Li, Xiang-Zhi Zhang, Wen-Zhe Ma, Ai-Jun Ma, Na Feng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Li HeSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Jing-Jing DuState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Jun-Jie ZhouSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Meng-Ting ChenSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Lu LuoSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Bao-Qiong LiSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Xiang-Zhi ZhangSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Wen-Zhe MaState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Ai-Jun MaSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Na FengSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.
Wuyi University · CNMacau University of Science and Technology · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melatonin (MT) is a hormone with antioxidant activity secreted by the pineal gland in the human brain, which is highly efficient in scavenging free radicals and plays an important role in the neuro-immuno-endocrine system. Emerging evidence showed that MT supplementation was a potential therapeutic strategy for Parkinson's disease (PD), which inhibits pathways associated with oxidative stress in PD. In this study, we reported a C7-selective olefination of melatonin under rhodium catalysis with the aid of P

Indexed as

antioxidant activityC. elegansderivative of melatoninParkinson’s diseasesynthesis

Identifiers

PMID35755259
PMCPMC9213837
OpenAlexW4285743188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.