Evidence map›Paper›PMID 35755195›Full record

ArticleRSC chemical biology2022

Chemical synthesis of

Nandarapu Kumarswamyreddy, Damodara N Reddy, D Miklos Robkis, Nao Kamiya, Ryoko Tsukamoto, Masahiro M Kanaoka, Tetsuya Higashiyama, Shunsuke Oishi, Jeffrey W Bode

Abstract read
In one paragraph

Article in RSC chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nandarapu KumarswamyreddyInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University Chikusa Nagoya 464-8601 Japan bode@itbm.nagoya-u.ac.jp oishi@itbm.nagoya-u.ac.jp.ORCID https://orcid.org/0000-0002-7640-1201
Damodara N ReddyInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University Chikusa Nagoya 464-8601 Japan bode@itbm.nagoya-u.ac.jp oishi@itbm.nagoya-u.ac.jp.ORCID https://orcid.org/0000-0001-9762-9160
D Miklos RobkisInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University Chikusa Nagoya 464-8601 Japan bode@itbm.nagoya-u.ac.jp oishi@itbm.nagoya-u.ac.jp.ORCID https://orcid.org/0000-0001-5958-5478
Nao KamiyaDivision of Biological Science, Graduate School of Science, Nagoya University Nagoya 464-0602 Japan.
Ryoko TsukamotoDivision of Biological Science, Graduate School of Science, Nagoya University Nagoya 464-0602 Japan.
Masahiro M KanaokaDivision of Biological Science, Graduate School of Science, Nagoya University Nagoya 464-0602 Japan.ORCID https://orcid.org/0000-0003-4913-6278
Tetsuya HigashiyamaInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University Chikusa Nagoya 464-8601 Japan bode@itbm.nagoya-u.ac.jp oishi@itbm.nagoya-u.ac.jp.ORCID https://orcid.org/0000-0002-7346-360X
Shunsuke OishiInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University Chikusa Nagoya 464-8601 Japan bode@itbm.nagoya-u.ac.jp oishi@itbm.nagoya-u.ac.jp.ORCID https://orcid.org/0000-0001-8807-9072
Jeffrey W BodeInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University Chikusa Nagoya 464-8601 Japan bode@itbm.nagoya-u.ac.jp oishi@itbm.nagoya-u.ac.jp.ORCID https://orcid.org/0000-0001-8394-8910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis of secreted cysteine-rich proteins (CRPs) is a long-standing challenge due to protein aggregation and premature formation of inter- and intramolecular disulfide bonds. Chemical synthesis provides reduced CRPs with a higher purity, which is advantageous for folding and isolation. Herein, we report the chemical synthesis of pollen tube attractant CRPs

Identifiers

PMID35755195
PMCPMC9175099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.