Evidence map›Paper›PMID 35755190›Full record

ArticleRSC chemical biology2022

Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin.

Jakob Leppkes, Nicole Dimos, Bernhard Loll, Thomas Hohmann, Michael Dyrks, Ariane Wieseke, Bettina G Keller, Beate Koksch

Open access · goldAbstract read
In one paragraph

Article in RSC chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Non-Canonical Amino Acids in Analyses of Protease Structure and Function.International journal of molecular sciences · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jakob LeppkesDepartment of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Freie Universität Berlin Arnimallee 20 14195 Berlin Germany beate.koksch@fu-berlin.de.ORCID https://orcid.org/0000-0002-2749-0543
Nicole DimosDepartment of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Structural Biochemistry, Freie Universität Berlin Takustr. 6 14195 Berlin Germany.ORCID https://orcid.org/0000-0001-5398-7310
Bernhard LollDepartment of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Structural Biochemistry, Freie Universität Berlin Takustr. 6 14195 Berlin Germany.ORCID https://orcid.org/0000-0001-7928-4488
Thomas HohmannDepartment of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Freie Universität Berlin Arnimallee 20 14195 Berlin Germany beate.koksch@fu-berlin.de.ORCID https://orcid.org/0000-0003-4623-5801
Michael DyrksDepartment of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Freie Universität Berlin Arnimallee 20 14195 Berlin Germany beate.koksch@fu-berlin.de.ORCID https://orcid.org/0000-0001-6432-6905
Ariane WiesekeDepartment of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Freie Universität Berlin Arnimallee 20 14195 Berlin Germany beate.koksch@fu-berlin.de.ORCID https://orcid.org/0000-0001-6982-329X
Bettina G KellerDepartment of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Freie Universität Berlin Arnimallee 22 14195 Berlin Germany.ORCID https://orcid.org/0000-0002-7051-0888
Beate KokschDepartment of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Freie Universität Berlin Arnimallee 20 14195 Berlin Germany beate.koksch@fu-berlin.de.ORCID https://orcid.org/0000-0002-9747-0740
Freie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substituting the P

Identifiers

PMID35755190
PMCPMC9175108
OpenAlexW4283643241

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.