ReviewRSC chemical biology2022
Laccase-mediated synthesis of bioactive natural products and their analogues.
Review in RSC chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 78 citations in OpenAlex.
- Efficient removal of methylene blue by sodium alginate microspheres immobilizing Aspergillus niger and FeBiodegradation · 2026Article
- Laccase-Mediated Fabrication of Food Packaging Films: A Critical Review of Functional Performance, Safety, and Industrial Viability.Biomolecules · 2026Review
- Article
- Article
- Laccase-Catalyzed Biotransformation of Dihydrostilbenes and Phenanthrenes: A Route to Novel Natural Product Derivatives.ACS omega · 2026Article
- Article
- Article
- Laccase immobilization on a natural lignocellulosic biomass support: optimization, characterization, and bisphenol A degradation.3 Biotech · 2026Article
- Research Progress of Laccase in Edible and Medicinal Fungi.Journal of fungi (Basel, Switzerland) · 2026Review
- The multifaceted physiological roles of fungal laccases.Communications biology · 2026Review
- Manganese-catalyzed dehydroxyamination of catechols for the synthesis of redox-active and heterocyclic scaffolds.RSC advances · 2026Article
- Laccase-Catalyzed Dimerization of Honokiol and Magnolol for Multitarget Metabolic Enzyme Inhibitors.Chembiochem : a European journal of chemical biology · 2026Article
- Synthetic Strategies and Biological Diversity of Biflavonoids: Current Status and Perspective.Molecules (Basel, Switzerland) · 2026Review
- Bacterial cytochrome P450 for oxidative halogenated biaryl coupling.ACS catalysis · 2026Article
- Bioconversion ofCurrent issues in molecular biology · 2025Article
- Specific Phenylpropanoid Oligomerization in a Neutral Environment by the Recombinant Alkaline Laccase fromBiomolecules · 2025Article
- Review on various activator-assisted polymer grafting techniques for smart drug delivery applications.RSC advances · 2025Review
- Benzoxanthenone Lignans Related to Carpanone, Polemanone, and Sauchinone: Natural Origin, Chemical Syntheses, and Pharmacological Properties.Molecules (Basel, Switzerland) · 2025Review
- Unlocking Lignin's Potential: Engineered Bacterial Laccases to Produce Biologically Active Molecules.ChemSusChem · 2025Article
- New synthetic approaches for the construction of 2-aminophenoxazinone architectures.RSC advances · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laccases are a class of multicopper oxidases that catalyse the one-electron oxidation of four equivalents of a reducing substrate, with the concomitant four-electron reduction of dioxygen to water. Typically, they catalyse many anabolic reactions, in which mostly phenolic metabolites were subjected to oxidative coupling. Alternatively, laccases catalyse the degradation or modification of biopolymers like lignin in catabolic processes. In recent years, laccases have proved valuable and green biocatalysts for synthesising compounds with therapeutic value, including antitumor, antibiotic, antimicrobial, and antioxidant agents. Further up to date applications include oxidative depolymerisation of lignin to gain new biomaterials and bioremediation processes of industrial waste. This review summarizes selected examples from the last decade's literature about the laccase-mediated synthesis of biologically active natural products and their analogues; these will include lignans and neolignans, dimeric stilbenoids, biflavonoids, biaryls and other compounds of potential interest for the pharmaceutical industry. In addition, a short section about applications of laccases in natural polymer modification has been included.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.