ReviewCureus2022
Is the Organ Care System (OCS) Still the First Choice With Emerging New Strategies for Donation After Circulatory Death (DCD) in Heart Transplant?
Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Review
- Recent perioperative challenges in anesthesia during expansion of heart transplantation.Journal of cardiothoracic surgery · 2026Review
- Alternative Preservation Strategies of Donation After Circulatory Death Hearts: Effect of Cold Ischemia Time Before Normothermic Machine Perfusion.Journal of the American Heart Association · 2026Article
- Heart Transplantation and Cold Ischemia: Towards Crossing the Border?Brazilian journal of cardiovascular surgery · 2026Article
- Optimizing Temperature in Ex Situ Heart Perfusion: A Comparative Review of Traditional and Novel Methods in Heart Transplantation.Journal of cardiovascular development and disease · 2026Review
- Article
- Article
- Correlation Between the Distance From Donors and Ischemic Time in Heart Transplantation of Korea and Its Clinical Impact.Journal of Korean medical science · 2025Article
- Cardiac preservation usingFrontiers in cardiovascular medicine · 2025Article
- Enhanced Donor Lung Viability During ProlongedTransplant international : official journal of the European Society for Organ Transplantation · 2025Article
- The Rapidly Evolving Landscape of DCD Heart Transplantation.Current cardiology reports · 2024Review
- Adult cardiac transplantation utilizing donors after circulatory death.Annals of cardiothoracic surgery · 2024Review
- Successful Resuscitation of Porcine Hearts After 12 and 24 h of Static Cold Storage With Normothermic Ex Situ Perfusion.Transplantation direct · 2024Article
- CPA toxicity screening of cryoprotective solutions in rat hearts.Cryobiology · 2024Article
- Acute rejection in donation after circulatory death (DCD) heart transplants.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024Article
- First-in-human beating-heart transplant.JTCVS techniques · 2023Article
- Ex-Vivo Preservation of Heart Allografts-An Overview of the Current State.Journal of cardiovascular development and disease · 2023Article
- Thoracic organ machine perfusion: A review of concepts with a focus on reconditioning therapies.Frontiers in transplantation · 2023Review
- Donation After Circulatory Death: A New Frontier.Current cardiology reports · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The scarcity of donor hearts continues to be a challenge in transplants for advanced heart failure patients. With an increasing number of patients on the waiting list for a heart transplant, the discrepancy in the number between donors and recipients is gradually increasing and poses a new challenge that plagues the healthcare systems when it comes to the heart. Several technologies have been developed to expand the donor pool in recent years. One such method is the organ care system (OCS). The standard method of organ preservation is the static cold storage (SCS) method which allows up to four hours of safe preservation of the heart. However, beyond four hours of cold ischemia, the incidence of primary graft dysfunction increases significantly. OCS keeps the heart perfused close to the physiological state beyond the four hours with superior results, which allows us to travel further and longer distances, leading to expansion in the donor pool. In this review, we discuss the OCS system, its advantages, and shortcomings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.