ArticleMedical physics2022
A minimum SNR criterion for computed tomography object detection in the projection domain.
Article in Medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- The Uncoupling of CT Dose and Noise.Radiology · 2026Article
- Electron Density Dual-energy CT for Liver Metastasis Detection Compared with Conventional and Virtual Monoenergetic Images at 40 keV.Current medical imaging · 2026Observational
- Comparative evaluation of iodinated, nanoparticle-based, and gadolinium-based contrast agents in computed tomography for small animals.PloS one · 2026Article
- Correlation between exposure (mAs) and image quality for a rapid cone-beam CT on a ring gantry linear accelerator.Journal of applied clinical medical physics · 2025Article
- Automated measurement of detectability index in CT imaging: Development and validation.Journal of applied clinical medical physics · 2025Article
- Lutetium-Based Nanoprobes for Radiosensitization with Immune Microenvironment Remodeling and NIR-II Fluorescence Imaging-Guided Surgery in Colorectal Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Development of optimised protocols for paediatric whole-body computed tomography examinations: a figure-of-merit approach.BMC medical imaging · 2025Article
- Spatial resolution improvements for photon counting detectors using coincidence counting and frequency weighted reconstruction.Medical physics · 2025Article
- Harnessing 3D microarchitecture of pterosaur bone using multi-scale X-ray CT for aerospace material design.Scientific reports · 2025Article
- Ultrasound-guided photoacoustic image annotation toolkit in MATLAB (PHANTOM) for preclinical applications.Photoacoustics · 2025Article
- Dichroism-sensitive photoacoustic imaging for in-depth estimation of the optic axis in fibrous tissue.Photoacoustics · 2025Article
- Relating human and AI-based detection limits in scanning electron microscopy dimensional metrology.Journal of micro/nanolithography, MEMS, and MOEMS : JM3 · 2025Article
- Impact of signal-to-noise ratio and contrast definition on the sensitivity assessment and benchmarking of fluorescence molecular imaging systems.Journal of biomedical optics · 2025Article
- Existence, uniqueness, and efficiency of numerically unbiased attenuation pathlength estimators for photon counting detectors at low count rates.Medical physics · 2024Article
- 3D printed phantom with 12 000 submillimeter lesions to improve efficiency in CT detectability assessment.Medical physics · 2024Article
- Photon Counting Computed Tomography for Accurate Cribriform Plate (Lamina Cribrosa) Imaging in Adult Patients.Tomography (Ann Arbor, Mich.) · 2024Article
- Application of learned ideal observers for estimating task-based performance bounds for computed imaging systems.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Ultrasound-guided Photoacoustic image Annotation Toolkit in MATLAB (PHANTOM) for preclinical applications.bioRxiv : the preprint server for biology · 2023Article
- A dense search challenge phantom fabricated with pixel-based 3D printing for precise detectability assessment.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundA common rule of thumb for object detection is the Rose criterion, which states that a signal must be five standard deviations above background to be detectable to a human observer. The validity of the Rose criterion in CT imaging is limited due to the presence of correlated noise. Recent reconstruction and denoising methodologies are also able to restore apparent image quality in very noisy conditions, and the ultimate limits of these methodologies are not yet known. PURPOSE: To establish a lower bound on the minimum achievable signal-to-noise ratio (SNR) for object detection, below which detection performance is poor regardless of reconstruction or denoising methodology.
methodsWe consider a numerical observer that operates on projection data and has perfect knowledge of the background and the objects to be detected, and determine the minimum projection SNR that is necessary to achieve predetermined lesion-level sensitivity and case-level specificity targets. We define a set of discrete signal objects
resultsWhen
conclusionsEven with perfect knowledge of the background and target objects, the ideal observer still requires an SNR of approximately 5. This is a lower bound on the SNR that would be required in real conditions, where the background and target objects are not known perfectly. Algorithms that denoise lesions with less than 5 projection SNR, regardless of the denoising methodology, are expected to show vanishing effects or false positive lesions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.