Evidence map›Paper›PMID 35754198›Full record

Trial reportJournal of periodontology2023

Patient-reported outcomes of palatal donor site healing using four different wound dressing modalities following free epithelialized mucosal grafts: A four-arm randomized controlled clinical trial.

Hussein S Basma, Muhammad H A Saleh, Ramzi V Abou-Arraj, Matthew Imbrogno, Andrea Ravida, Hom-Lay Wang, Peng Li, Nicolaas Geurs

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of periodontology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06116539 phase1unknown statusnot on this mapstarted 2024, after this paper: background citation

Multicenter Randomized Clinical Trial of the Use of Cyanoacrylate in Healing and Pain in the Palatal Donor Site of Connective Tissue Grafts

TypeinterventionalSponsorAlfonso X El Sabio UniversityRan2024 to 2024Enrolled80ConditionsPain, Postoperative, Healing Surgical WoundsArmsCyanoacrylate, Suture
NCT07367165 nacompletednot on this map

Improving Palatal Donor Site Healing and Reducing Postoperative Morbidity With Concentrated Growth Factor and Collagen Fleece: Randomized Controlled Clinical Study

TypeinterventionalSponsorInonu UniversityRan2023 to 2026Enrolled38ConditionsWound HealingArmsConcentrated Growth Factor (CGF), Collagen Fleece (CF), Collagen Sponge (Control)
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hussein S BasmaDepartment of Periodontics, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-0631-7220
Muhammad H A SalehDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Ramzi V Abou-ArrajDepartment of Periodontics, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-3552-6603
Matthew ImbrognoDepartment of Periodontics, University of Louisville School of Dentistry, Louisville, Kentucky, USA.
Andrea RavidaDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Hom-Lay WangDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.ORCID 0000-0003-4238-1799
Peng LiSchool of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Nicolaas GeursDepartment of Periodontics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
University of Alabama at Birmingham · USUniversity of Michigan · USUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to compare the effects of four different commonly used wound dressings in improving patient reported outcomes (PROMS) after free epithelialized mucosal grafts (FEGs) harvesting.

methodsFollowing 72 FEGs harvesting from 72 patients, patients were assigned into four groups. CONTROL: collagen plug + sutures (CPS); test: collagen plug with cyano-acrylate (CPC), platelet rich fibrin (PRF) + sutures, or palatal stent only (PS). Patients were observed for 14 days, with evaluation of pain level utilizing the visual analog scale, number of analgesics consumed, need for additional analgesics, amount of swelling, amount of bleeding, activity tolerance, and willingness for retreatment.

resultsCompared to the control group all test groups indicated significant lower pain perception (P < 0.0001), lower analgesic consumption (P < 0.0001), and higher willingness for retreatment (P < 0.0001), while no statistically significant differences among test groups were observed. There were no statistically significant differences in amount of day-by-day swelling, bleeding, and activity tolerance among four groups. Compared to other groups, the PS had the lowest overall pain scores (over the 14-day period). Palatal thickness, graft length, graft width, and graft thickness did not appear to affect patient morbidity (P > 0.05).

conclusionsAll interventions significantly decreased pain perception compared to a hemostatic collagen sponge alone over the palatal donor site after FEG surgery. In the first few days after surgery, the use of a palatal stent seemed to be associated with less overall pain, pain pills consumed, and higher willingness of doing the same procedure again.

Indexed as

CollagenWound HealingAnalgesicsBandagesHumansPalatePostoperative PainAnalgesicsCollagenpainpalatesuturestissue adhesiveswound healing

Identifiers

PMID35754198
PMCPMC10087796
OpenAlexW4283591951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.