Evidence map›Paper›PMID 35754143›Full record

ArticleMagnetic resonance in medicine2022

Accelerated dual-venc 4D flow MRI with variable high-venc spatial resolution for neurovascular applications.

Maria Aristova, Jianing Pang, Yue Ma, Liliana Ma, Haben Berhane, Vitaliy Rayz, Michael Markl, Susanne Schnell

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Fully self-gated dual-venc five-dimensional flow magnetic resonance imaging for simultaneous imaging of the cardiovascular and portal venous systems: A feasibility study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. 4D flow MRI velocity uncertainty quantification.Magnetic resonance in medicine · 2025
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria AristovaDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-9330-9415
Jianing PangDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Yue MaDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Liliana MaDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0001-8834-8519
Haben BerhaneDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-1381-7373
Vitaliy RayzWeldon School of Biomedical Engineering, Purdue University College of Engineering, West Lafayette, Indiana, USA.
Michael MarklDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Susanne SchnellDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008152 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARDEHALI, HOSSEIN · 1987 to 2021
$24.0M
Medical Scientist Training ProgramT32GM144295 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ALAN R HAUSER · 2022 to 2026
$9.1M
Non-invasive Evaluation of Intracranial Atherosclerotic Disease Using Hemodynamic BiomarkersR01HL149787 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ANSARI, SAMEER A, MARKL, MICHAEL · 2020 to 2023
$1.9M
Multi-modality 4D Flow MRI data enhancement for quantification of cerebral aneurysms hemodynamicsR21NS106696 · NINDS · PURDUE UNIVERSITY · PI RAYZ, VITALIY L, SCHNELL, SUSANNE · 2018 to 2019
$419k
4D Flow MRI-based assessment of atrial fibrillationF30HL137279 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MA, LILIANA · 2017 to 2020
$189k
4D Flow MRI for characterization of brain arteriovenous malformationsF30HL140910 · NHLBI · NORTHWESTERN UNIVERSITY · PI ARISTOVA, MARIA · 2018 to 2021
$181k
NHLBI NIH HHS F30 HL137279NHLBI NIH HHS F30 HL140910NHLBI NIH HHS R01 HL149787NIGMS NIH HHS T32 GM008152NIGMS NIH HHS T32 GM144295NIH HHS F30 HL137279NIH HHS F30 HL140910NIH HHS R21 NS106696NIH HHS T32 GM815229NINDS NIH HHS R21 NS106696
6 · The paper itself

Abstract

purposeDual-velocity encoded (dual-venc or DV) 4D flow MRI achieves wide velocity dynamic range and velocity-to-noise ratio (VNR), enabling accurate neurovascular flow characterization. To reduce scan time, we present interleaved dual-venc 4D Flow with independently prescribed, prospectively undersampled spatial resolution of the high-venc (HV) acquisition: Variable Spatial Resolution Dual Venc (VSRDV).

methodsA prototype VSRDV sequence was developed based on a Cartesian acquisition with eight-point phase encoding, combining PEAK-GRAPPA acceleration with zero-filling in phase and partition directions for HV. The VSRDV approach was optimized by varying z, the zero-filling fraction of HV relative to low-venc, between 0%-80% in vitro (realistic neurovascular model with pulsatile flow) and in vivo (n = 10 volunteers). Antialiasing precision, mean and peak velocity quantification accuracy, and test-retest reproducibility were assessed relative to reference images with equal-resolution HV and low venc (z = 0%).

resultsIn vitro results for all z demonstrated an antialiasing true positive rate at least 95% for

conclusionVSRDV allows up to 34.8% scan time reduction compared to PEAK-GRAPPA accelerated DV 4D Flow MRI, enabling large spatial coverage and dynamic range while maintaining VNR and velocity measurement accuracy.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingBlood Flow VelocityHumansPhantoms, ImagingPulsatile FlowReproducibility of Results4D flowaccelerationacquisitiondual-vencneurovascular

Identifiers

PMID35754143
PMCPMC9392495

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.