Evidence map›Paper›PMID 35754021›Full record

Observational studyRespiratory research2022

Use of high flow nasal cannula in patients with acute respiratory failure in general wards under intensivists supervision: a single center observational study.

Sebastiano Maria Colombo, Vittorio Scaravilli, Andrea Cortegiani, Nadia Corcione, Amedeo Guzzardella, Luca Baldini, Elisa Cassinotti, Ciro Canetta, Stefano Carugo, Cinzia Hu and 8 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Respiratory research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Sebastiano Maria ColomboDepartment of Anaesthesia and Intensive Care Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Sforza, 35, 20122, Milan, Lombardia, Italy.
Vittorio ScaravilliDepartment of Anaesthesia and Intensive Care Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Sforza, 35, 20122, Milan, Lombardia, Italy.
Andrea CortegianiDepartment of Surgical, Oncological and Oral Science (Di.Chir.On.S.), University of Palermo, Palermo, Sicilia, Italy.
Nadia CorcioneRespiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy.
Amedeo GuzzardellaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Lombardia, Italy.
Luca BaldiniDepartment of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy.
Elisa CassinottiDepartment of Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy.
Ciro CanettaDepartment of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy.
Stefano CarugoDepartment of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy.
Cinzia HuDepartment of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy.
Anna Ludovica FracanzaniDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Lombardia, Italy.
Ludovico FurlanDepartment of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy.
Maria Chiara PaleariDepartment of Anaesthesia and Intensive Care Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Sforza, 35, 20122, Milan, Lombardia, Italy.
Alessandro GalazziHealthcare Profession Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Lombardia, Italy.
Paola TagliabueDepartment of Anaesthesia and Intensive Care Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Sforza, 35, 20122, Milan, Lombardia, Italy.
Flora PeyvandiDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Lombardia, Italy.
Francesco BlasiDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Lombardia, Italy.
Giacomo GrasselliDepartment of Anaesthesia and Intensive Care Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Sforza, 35, 20122, Milan, Lombardia, Italy. giacomo.grasselli@unimi.it.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITLombardia Informatica (Italy) · ITAzienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · IT

Funding

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Ricerca Corrente 2021- Ottimizzazione del supporto respiratorio e gestione del paziente con insufficienza respiratoria
6 · The paper itself

Abstract

backgroundFew data exist on high flow nasal cannula (HFNC) use in patients with acute respiratory failure (ARF) admitted to general wards. RATIONALE AND

objectivesTo retrospectively evaluate feasibility and safety of HFNC in general wards under the intensivist-supervision and after specific training.

methodsPatients with ARF (dyspnea, respiratory rate-RR > 25/min, 150 < PaO

results150 patients (81 male, age 74 [60-80] years, SOFA 4 [2-4]), 123 with de-novo ARF underwent HFNC with flow 60 L/min [50-60], FiO

conclusionIn patients with mild-moderate ARF admitted to general wards, the use of HFNC after an initial training and daily supervision by intensivists was feasible and seemed safe. HFNC was effective in improving comfort, dyspnea, and respiratory rate without effects on gas exchanges. Trial registration This is a single-centre, noninterventional, retrospective analysis of clinical data.

Indexed as

Noninvasive VentilationRespiratory Distress SyndromeRespiratory InsufficiencyAgedCannulaDyspneaHumansMaleOxygenOxygen Inhalation TherapyPatients' RoomsRetrospective StudiesOxygenAHRFARFGeneral-wardsHFNCICU-supervisionSafety

Identifiers

PMID35754021
PMCPMC9233759
OpenAlexW4283528939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.