ArticleChest2022
Alveolar Dead Space Is Augmented During Exercise in Patients With Heart Failure With Preserved Ejection Fraction.
Article in Chest, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Ventilatory limitation to exercise in patients with HFpEF and obesity: No room to breathe.Respiratory physiology & neurobiology · 2026Trial
- Heart-Lung Interactions in HFpEF: Dynamic Hyperinflation and Exercise PCWP.JACC. Heart failure · 2025Trial
- Oxygen cost of breathing and its association with dyspnea in older patients with heart failure with preserved ejection fraction and obesity.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Organ cross-talk: molecular mechanisms, biological functions, and therapeutic interventions for diseases.Signal transduction and targeted therapy · 2026Review
- Exercise-induced arterial hypoxaemia in patients with heart failure with preserved ejection fraction.The Journal of physiology · 2025Article
- Insights Into the Role of Obesity in Heart Failure With Preserved Ejection Fraction: Pathophysiology and Management.The Canadian journal of cardiology · 2025Review
- Physiologic Phenotyping of Responses to Exercise and Activity in Heart Failure.Circulation research · 2025Review
- Pulmonary gas exchange in relation to exercise pulmonary hypertension in patients with heart failure with preserved ejection fraction.The European respiratory journal · 2025Article
- Respiratory symptom perception during exercise in patients with heart failure with preserved ejection fraction.Respiratory physiology & neurobiology · 2024Article
- Ventilatory limitations in patients with HFpEF and obesity.Respiratory physiology & neurobiology · 2023Article
- Article
- Inhibiting regional sweat evaporation modifies the ventilatory response to exercise: interactions between core and skin temperature.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPatients with heart failure with preserved ejection fraction (HFpEF) exhibit many cardiopulmonary abnormalities that could result in V˙/Q˙ mismatch, manifesting as an increase in alveolar dead space (VD RESEARCH QUESTION: Do patients with HFpEF develop VD STUDY DESIGN AND
methodsTwenty-three patients with HFpEF and 12 control participants were studied. Gas exchange (ventilation [V˙
resultsVD
interpretationThese data suggest that the increase in V˙/Q˙ mismatch may be explained by increases in VD
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.