Evidence map›Paper›PMID 35753241›Full record

ArticleJournal of psychiatric research2022

A prospective study of transdiagnostic psychiatric symptoms associated with burnout and functional difficulties in COVID-19 frontline healthcare workers.

Lorig Kachadourian, James Murrough, Carly Kaplan, Sabrina Kaplan, Jordyn Feingold, Adriana Feder, Dennis Charney, Steven Southwick, Lauren Peccoralo, Jonathan DePierro and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lorig KachadourianVA Connecticut Healthcare System, West Haven, CT, United States. Electronic address: lorig.kachadourian@va.gov.
James MurroughMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Carly KaplanMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Sabrina KaplanMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Jordyn FeingoldMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Adriana FederMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Dennis CharneyMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Steven SouthwickYale University School of Medicine, United States.
Lauren PeccoraloMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Jonathan DePierroMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Jonathan RippMount Sinai School of Medicine, Icahn School of Medicine at Mount Sinai, United States.
Robert PietrzakYale School of Medicine, Yale University School of Medicine, United States.
Icahn School of Medicine at Mount Sinai · USYale University · USVA Connecticut Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFrontline healthcare workers (FHCWs) responding to the COVID-19 pandemic develop posttraumatic stress disorder (PTSD), major depressive disorder (MDD) and generalized anxiety disorder (GAD) symptoms. Such symptoms are associated with burnout, occupational and relational difficulties. In the current study, we examined the prospective association between acute transdiagnostic COVID-19-related PTSD, MDD, and GAD symptoms at pandemic outset, and burnout and functional difficulties several months later in FHCWs in New York City.

methodsWave 1 symptoms of COVID-19-related PTSD, MDD, and GAD, were assessed in 787 FHCWs from April 14 to May 11th, 2020. Burnout and occupational difficulties were assessed at wave 1 and wave 2, approximately 7 months later.

resultsAfter adjusting for wave 1 burnout, wave 1 MDD symptoms, particularly sleep difficulties, loss of interest, and feeling tired/having little energy, collectively explained 42% incremental variance in this outcome. After adjusting for wave 1 work difficulties, MDD and PTSD symptoms, particularly feeling tired/having little energy, loss of interest, and negative expectations of self/world, collectively explained 42% incremental variance in this outcome. After adjusting for wave 1 relationship difficulties, MDD, GAD, and PTSD symptoms, particularly depressed mood, irritability, and appetite disturbance, explained 26% incremental variance in this outcome.

conclusionsResults highlight psychiatric symptoms assessed during the acute phase of the COVID-19 pandemic that may help predict burnout and work and relationship difficulties in FHCWs. Early interventions aimed at ameliorating transdiagnostic symptoms of MDD, PTSD, and GAD may help mitigate risk for burnout and functional difficulties in this population.

Indexed as

Burnout, ProfessionalCOVID-19Major Depressive DisorderStress Disorders, Post-TraumaticHealth PersonnelHumansPandemicsProspective StudiesBurnoutFrontline healthcare workersMental health impactOccupational outcomesRelationship outcomesSARS COVID-19

Identifiers

PMID35753241
PMCPMC9181632
OpenAlexW4281853065

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.