Evidence map›Paper›PMID 35753155›Full record

ArticleJournal of infection and public health2022

Factors associated with mortality, length of hospital stay and diagnosis of COVID-19: Data from a field hospital.

Vanessa da Costa Sousa, Mayara Calixto da Silva, Matheus Pereira de Mello, João Antonio Matheus Guimarães, Jamila Alessandra Perini

Abstract read
In one paragraph

Article in Journal of infection and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vanessa da Costa SousaNational School of Public Health, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil. Electronic address: vanessamedrj@gmail.com.
Mayara Calixto da SilvaNational School of Public Health, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil; Pharmaceutical Sciences Research Laboratory (LAPESF), State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil. Electronic address: mayaracx_2010@hotmail.com.
Matheus Pereira de MelloPharmaceutical Sciences Research Laboratory (LAPESF), State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil. Electronic address: matheuspereira9.mp@gmail.com.
João Antonio Matheus GuimarãesNational Institute of Traumatology and Orthopaedics (INTO), Research Division of INTO, Rio de Janeiro, RJ, Brazil. Electronic address: jmatheusguimaraes@gmail.com.
Jamila Alessandra PeriniNational School of Public Health, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil; Pharmaceutical Sciences Research Laboratory (LAPESF), State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil; National Institute of Traumatology and Orthopaedics (INTO), Research Division of INTO, Rio de Janeiro, RJ, Brazil. Electronic address: jamilaperini@yahoo.com.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the pandemic of COVID-19, phylogenetic changes have been observed in the characteristics of the virus, in the diagnosis and treatment of the disease. The clinical course and the severe form of the disease depends on several factors. This study characterized the beginning setting for patient care of COVID-19 in a referral center in one of the main capital cities of Brazil. In addition, were evaluated the factors associated with mortality, length of stay, and diagnostic outcome.

methodsA cross-sectional study was conducted during May 2020 (n = 1100). The association of the variables with outcome was evaluated by a multivariable logistic regression model, using odds ratios (OR) and 95 % confidence intervals (CI).

resultsOverall, 76 % of patients were COVID-19 positive, and 70 % were diagnosed by RT-qPCR. The majority were male (56 %), and over 52 years old (74 %), 68 % had hypertension, 44 % had diabetes mellitus, and 32 % were obese. The mean length of stay was 10 ± 8 days, which was higher in the 34 % who died (≥14; OR=2; 95 %CI=1.4-4) and who had hypertension (OR=2; 95 %CI=1.3-3) (P < 0.001). The mean length of stay was also higher (P = 0.008) for those patients with pulmonary impairment ≥ 50 % (10.72 ± 8.24), than those with< 50 % (8.98 ± 6.81). Age (>62 and 65 years) was associated with longer hospitalization (OR=2; 95 %CI=1.4-3) and death (OR=6; 95 %CI=3-11). The time of sample collection for RT-qPCR was different between positive and negative tests (P = 0.001), with the time of 4-10 days showing a greater chance for virus detection (OR=2.9; 95 %CI=1.6-5).

conclusionDeath was associated with age and pulmonary impairment. The length of hospitalization was associated with age, hypertension, pulmonary impairment and death. The time of sample collection to perform RT-qPCR and the rapid test was associated with a positive result for COVID-19. These results highlight the ongoing challenge of diagnosing, treating, and mitigating the effects caused by the COVID-19 pandemic.

Indexed as

COVID-19HypertensionAgedCross-Sectional StudiesFemaleHospitalizationHumansLength of StayMaleMiddle AgedMobile Health UnitsPandemicsPhylogenyRetrospective StudiesRisk FactorsSARS-CoV-2BrazilCOVID-19DiagnosisMortalityRisk factors

Identifiers

PMID35753155
PMCPMC9214823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.