Evidence map›Paper›PMID 35753016›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2022

Cholinergic brain network deficits associated with vestibular sensory conflict deficits in Parkinson's disease: correlation with postural and gait deficits.

Nicolaas I Bohnen, Prabesh Kanel, Stiven Roytman, Peter J H Scott, Robert A Koeppe, Roger L Albin, Kevin A Kerber, Martijn L T M Müller

Open access · greenAbstract read
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Beyond motor: a systematic review of multisensory integration deficits in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Pooled it
  2. Review
  3. Article
  4. Cholinergic System Changes in Dopa-Unresponsive Freezing of Gait in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Nicolaas I BohnenDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA. nbohnen@umich.edu.ORCID 0000-0003-0352-6414
Prabesh KanelDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Stiven RoytmanDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Peter J H ScottDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Robert A KoeppeDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Roger L AlbinDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Kevin A KerberDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Martijn L T M MüllerDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · US

Funding

Tomography and Data AnalysisP01NS015655 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FREY, KIRK A. · 1985 to 2012
$13.0M
Udall Catalyst Research Project: Retrosplenial Cholinergic and Attentional-Motor Integration DysfunctionP50NS123067 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2021 to 2025
$11.6M
Public Outreach and Education CoreP50NS091856 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2014 to 2019
$10.1M
Central cholinergic presbyvestibulopathy network changes and imbalance in Parkinson's disease and older personsR01AG073100 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOHNEN, NICOLAAS IDA · 2021 to 2025
$3.0M
Hyposmia, Cholinergic Denervation and Incipient Cognitive Decline in PDR01NS070856 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOHNEN, NICOLAAS IDA · 2010 to 2014
$1.9M
Amyloidopathy, cholinopathy, dopamine responsiveness and freezing of gait in PDI01RX001631 · VA · VETERANS HEALTH ADMINISTRATION · PI BOHNEN, NICOLAAS IDA · 2016 to 2020
–
Vestibulopathy, imbalance and gait disturbances in Parkinson diseaseI01RX003397 · VA · VETERANS HEALTH ADMINISTRATION · PI Nicolaas Ida Bohnen · 2021 to 2026
–
NIA NIH HHS R01 AG073100NINDS NIH HHS P01 NS015655NINDS NIH HHS P50 NS091856NINDS NIH HHS P50 NS123067NINDS NIH HHS R01 NS070856RRD VA I01 RX001631RRD VA I01 RX003397
6 · The paper itself

Abstract

To examine regional cerebral vesicular acetylcholine transporter (VAChT) ligand [

Indexed as

Gait Disorders, NeurologicParkinson DiseaseAgedBrainCholinergic AgentsFemaleGaitHumansMaleMiddle AgedVesicular Acetylcholine Transport ProteinsCholinergic AgentsVesicular Acetylcholine Transport ProteinsFallsFreezing of gaitMedial geniculate nucleusParkinson’s diseasePostural controlVestibularVestibular sensory conflict

Identifiers

PMID35753016
PMCPMC9308723
OpenAlexW4283519007

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.