Evidence map›Paper›PMID 35752993›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2022

Risk factors for the failure of endoscopic resection of gastric submucosal tumors: a long-term retrospective case-control study.

Yuzhu Yuan, Lixin Sun, Xiaoying Zhou, Han Chen, Xinmin Si, Weifeng Zhang, Yun Wang, Bixing Ye, Nana Tang, Guoxin Zhang and 3 more

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Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuzhu Yuan *Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, 210009, China.
Lixin Sun *Jiangsu Center for Pharmacodynamics Research and Evaluation, China Pharmaceutical University, Nanjing, 210009, China.
Xiaoying Zhou *Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Han ChenDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Xinmin SiDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Weifeng ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Yun WangDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Bixing YeDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Nana TangDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Guoxin ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Xueliang LiDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Hongjie ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China.
Chunhua JiaoDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, 300# Guangzhou road, Nanjing, 210029, China. jch0409@163.com.ORCID 0000-0001-6562-0516

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEndoscopic resection (ER) is an effective treatment method for gastric submucosal tumors (G-SMTs), but endoscopic resection failure requires emergency surgery. The purpose of this study was to assess potential risk factors for endoscopic resection failure.

methodsA total of 1041 patients with G-SMT undergoing endoscopic resection were enrolled. Twenty-five patients in whom endoscopic resection failed, requiring a transition to surgery midway through the operation, were included in the failed group, and 1016 patients who received successful endoscopic resection were included in the successful endoscopic resection group. Baseline and lesion characteristics were recorded, and the differences in tumor characteristics and risk factors for resection failure of G-SMT were analyzed. Sensitivity analysis was performed to detect the stability of the indicator.

resultsOf the 1041cases included, there were 25 cases (2.4%) of failed endoscopic resection. Binary logistic analysis showed that the independent risk factors included tumors originating from deep muscularis propria(OR = 14.42, 95% CI 4.47-46.52), size > 3 cm (OR = 7.75, 95% CI 2.64-22.70), exophytic growth pattern (OR = 4.98, 95% CI 1.62-15.29), endoscopist with less experience (OR = 5.99, 95% CI 1.07-12.19), and irregular borders (OR = 4.13, 95% CI 1.40-12.19). The stable risk factors were tumors size, tumor origin and growth pattern according to sensitivity analysis.

conclusionsTumors originating from the deep muscularis propria, tumor size > 3 cm, endoscopists with less experience, an exophytic growth pattern, and irregular boundaries were found to be independent risk factors for endoscopic resection failure. To reduce the risk of endoscopic resection failure, physicians should carefully evaluate G-SMT characteristics preoperative.

Indexed as

Endoscopic Mucosal ResectionStomach NeoplasmsCase-Control StudiesGastric MucosaGastroscopyHumansRetrospective StudiesRisk FactorsTreatment OutcomeCase–control studyEndoscopic resectionGastric submucosal tumorsRisk factors

Identifiers

PMID35752993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.